南昌地区糖尿病足流行病学调查及相关危险因素分析  

The Epidemic Investigation and the Risk Factors of Diabetic Foot in Nanchang

作　　者：沈浩[1] 陆君[1] 姜玲 胡玲[1] 孙掌花[1] 

机构地区：[1]南昌大学第三附属医院,南昌330008 [2]江西省宜春市第一医院,宜春336000

出　　处：《江西中医学院学报》2013年第4期14-16,42,共4页Journal of Jiangxi College of Traditional Chinese Medicine

摘　　要：目的:针对南昌地区2型糖尿病(T2DM)患者糖尿病足(DF)发生率进行调查并分析其相关危险因素,为临床防治DF提供依据。方法:收集2000例住院的2型糖尿病患者,随机选取其中376例诊断为T2DM的患者按有无糖尿病足分为糖尿病足组(DF组)和非糖尿病足组(NDF组),搜集并记录所有患者的临床资料及实验室指标,比较2组危险因素之间的差异。结果:2组SBP、DBP、2hPG、HbA1c、LDL、FIB、SCr、BUN、总蛋白、白蛋白、尿微量白蛋白、ABI、TcPO2、VPT等因素差异有统计学意义(P<0.05);BMI、FPG、HDL、TC、TG等因素差异无统计学意义(P>0.05)。多因素非条件Logistic回归分析显示,糖尿病病程、HbAlc、FIB、白蛋白、ABI、TcPO2等是2型糖尿病发生糖尿病足的独立危险因素。结论:加强糖尿病宣教,做好足部护理,长期严格控制血糖,调节血压、血脂、血纤维蛋白原的失衡,抗动脉粥样硬化、抗凝、扩张血管、改善局部供血及抗感染等综合治疗,同时积极治疗糖尿病各种慢性并发症,能有效预防糖尿病足的发生。As a Aim： Investigate the epidemic situation in Nanchang, and analysis its relative risk factors.Methods： 376 patients were randomly chose from 2000 with type 2 diabetes in in-patient department. 188 patients with diabetic foot were divided into the diabetic foot group（DFG）, 188 diabetic patients without diabetic foot were divided into the diabetic foot group（NDFG）. All the patients were checked on the albumin, SBP, DBP, 2hPG, HbAlc, LDL, FIB, SCr, BUN, BMI, FPG, HDL, TC, TG, ABI, TcPO2 and VPT.Results： There were statistically significant difference in age, course, albumin, SBP, DBP, 2hPG, HbAlc, LDL, FIB, SCr, BUN, ABI, TcPO2 and VPT. Multiple factor non conditional logistic regression analysis showed that the course of T2DM, HbAlc, FIB, total protein, albumin, urinary albumin, ABI and TcPO2 are the independent risk factors for diabetic foot. Conclusions： The diabetic foot can be prevented by controlling strictly glycemia, blood pressure and fibrinogen.

关 键 词：糖尿病足 流行病学调查 危险因素 

分 类 号：R587.2[医药卫生—内分泌]