自拟健脾燥湿汤对肥胖型2型糖尿病患者胰岛素抵抗与超敏C反应蛋白的影响  

Influence of Strengthening Spleen and Eliminating Dampness Decoction on Endomorph Insulin Resistance of Type 2 Tiabetes and High Sensitivity C Reactive Protein

作　　者：韩琳[1] 殷豪良 张慧[1] 贺支支[1] 

机构地区：[1]江西中医学院附属医院,南昌330006 [2]江西南昌桑海开发区医院,南昌330115

出　　处：《江西中医学院学报》2013年第4期26-28,共3页Journal of Jiangxi College of Traditional Chinese Medicine

基　　金：江西省卫生厅科研课题(项目编号:2011A023);江西省教育厅科研课题(项目编号:GJJ12524)

摘　　要：目的:探讨中药自拟健脾燥湿汤对肥胖型2型糖尿病胰岛素抵抗与超敏C反应蛋白的影响。方法:将60名肥胖型2型糖尿病患者分为治疗组与对照组各30例,治疗组予自拟健脾燥湿汤联合二甲双胍治疗,对照组予二甲双胍治疗,均治疗6个月,观察治疗前后患者血清超敏C反应蛋白及相关代谢指标的变化。结果:2组治疗前后均有明显下降(P<0.05),且治疗组疗效明显优于对照组(P<0.05)。结论:对于肥胖型2型糖尿病患者,健脾燥湿汤联合二甲双胍更能明显地改善胰岛素抵抗及β细胞功能而降低血糖,同时又能明显地减轻体重,改善脂代谢,还具有更强的抗炎作用。Objective： To investigate the relationship between obesity and spleen dampness Decoction Treatment of insulin resistance of type 2 diabetes and high sensitivity C reactive protein. Methods： Patients with 60 obese type 2 diabetes were divided into two groups, spleen dampness decoction combined with metformin in the treatment of 30 cases, 30 cases of metformin treatment, treatment for six months, changes were observed before and after treatment in patients with serum high sensitivity C reactive protein and related metabolism indexes. Results： the two groups before and after treatment were significantly decreased （P〈0.05）, and the effect of the treatment group was significantly better than the control group （P〈0.05）.

关 键 词：肥胖型2型糖尿病 胰岛素抵抗 超敏C反应蛋白 健脾燥湿汤 

分 类 号：R587.1[医药卫生—内分泌] R589[医药卫生—内科学]