仙慈丹的质量标准研究  

Study of Quality Standard for Xiancidan

作　　者：鲁芹飞[1] 黄松[1,2] 朱德全[1] 黄斌[1] 赖小平[1,2] 

机构地区：[1]广州中医药大学,广州510006 [2]东莞广州中医药大学中医药数理工程研究院,广东东莞523808

出　　处：《中国药师》2013年第11期1644-1647,共4页China Pharmacist

基　　金：广东省科技计划项目(编号:2010B030700001)

摘　　要：目的：建立仙慈丹（XCD）的质量标准。方法：采用薄层色谱法进行定性鉴别,RP-HPLC法进行定量测定。结果：建立了半枝莲、三七、姜黄、苏木的薄层色谱鉴别方法,建立了野黄芩苷的测定方法,野黄芩苷的加样回收率为100.55%（RSD为1.54%,n=6）,线性范围为0.032~0.481μg（r=0.999 9）。结论：所建立的定性、定量方法简便、准确、重复性好,专属性强,可较全面地控制仙慈丹的质量。Objective： To establish the quality standard for Xiancidan. Method： TLC was used to qualitatively differentiate the material medicines; and RP-HPLC was used to detect the content of scutellarin. Result： The TLC identification method for ScuteUaria barbara, Caesalpinia sappan, Curcuma longa and Panax notoginseng （ Burk. ） F. H. Chen in the preparation was established. The con- tent of scutellarin was linear within the range of 0.032-0. 481 ~g（ r = 0. 999 9）. The average recovery was 100.55%. Conclusion： The methods are easily operated with promising specificity and repeatability, and convenient, reliable and accurate in the quality con- trol of Xiancidan

关 键 词：仙慈丹 质量标准 薄层色谱 高效液相色谱法 野黄芩苷 

分 类 号：TQ460.72[医药卫生—药物分析学]