多器官功能障碍综合征多重耐药菌病原学分析  

Etiological Analysis of Multiple Organ Dysfunction Syndrome with Multiple Drug-resistant Bacterial Infections

作　　者：李青[1] 詹以安[2] 王联群[2] 朱峰[2] 曾振国[2] 刘芬[2] 丁成志[2] 钱克俭[2] 

机构地区：[1]江西省人民医院药剂科 [2]南昌大学第一附属医院重症医学科,南昌330006

出　　处：《实用临床医学（江西）》2013年第9期1-4,共4页Practical Clinical Medicine

基　　金：江西省卫生厅科技计划(20131021)

摘　　要：目的探讨多器官功能障碍综合征(MODS)患者发生多重耐药菌感染的病原学分布及耐药情况。方法回顾性分析149例MODS患者的临床资料。对临床送检标本中多重耐药菌的病原菌分布、常见多重耐药菌菌株的耐药情况进行统计和分析。结果在149例患者中分离出226株细菌,其中多重耐药菌117株,在多重耐药菌株中排名前5位依次是:鲍曼不动杆菌(33.71%)、铜绿假单胞菌(15.73%)、肺炎克雷伯杆菌(13.48%)、大肠埃希氏菌(7.87%)、金黄色葡萄球菌(6.84%)。结论 MODS患者中多重耐药菌所占比例较高,对多种抗生素呈广泛的不同程度的耐药。Objective To investigate the etiological distribution and drug resistance of multiple drug-resistant bacterial infections in patients with multiple organ dysfunction syndrome （MODS）. Methods Clinical data of 149 patients with MODS were retrospectively analyzed. The distribution and drug resistance of common multiple drug-resistant bacteria were counted and analyzed. Results A total of 226 bacterial strains were isolated from patients, including 117 multiple drug-resistant strains. The top five drug-resistant strains were： Acinetobacter baumannii （33.71%）, Pseudomonas aeruginosa （15.73%）, Klebsiella pneumoniae（13.48%）, Escherichia coli（7.87%）, and Staphylococcus aureus（6.84%）. Conclusion The prevalence of multiple drug-resistant bacterial infections is high among MODS patients. These multiple drug-resistant strains attribute widely different degrees of resistance to many antibiotics.

关 键 词：多器官功能障碍综合征 多重耐药菌感染 病原学 

分 类 号：R446.5[医药卫生—诊断学]