神经节苷酯联合高压氧治疗颅脑外伤疗效观察  

Efficacy of ganglioside combined with hyperbaric oxygen on traumatic brain injury

作　　者：徐建昌[1] 刘文广[1] 韩辉[1] 齐亮[1] 

机构地区：[1]江苏淮安市第二人民医院神经外科,淮安223002

出　　处：《中国实用神经疾病杂志》2013年第21期35-36,共2页Chinese Journal of Practical Nervous Diseases

摘　　要：目的观察神经节苷酯联合高压氧治疗颅脑外伤的临床疗效。方法将我院2010-02—2011-02收治78例颅脑外伤患者随机分为2组,对照组39例常规治疗,观察组39例在常规治疗基础上给予神经节苷酯联合高压氧治疗,观察2组治疗效果。结果观察组有效率明显的优于对照组,而病死率和重残率则明显低于对照组,差异统计学有意义(P<0.05)。结论神经节苷酯联合高压氧治疗颅脑外伤患者具有较好的临床效果,降低了病死率和重残率,值得临床应用推广。Objective To observe clinical efficacy of the the ganglioside combined with hyperbaric oxygen on traumatic brain injury. Methods Between February 2010 to February 2011, 78 patients with traumatic brain injury patients from our hospital were randomly divided into two groups, the control group of 39 patients were treated with conventional treatment, while the observation group of 39 cases patients were given the ganglioside combined with hyperbaric oxygen based on conven- tional treatment. The treatment effect in both groups were observed. Results The treatment efficiency of the observation group was significantly better than that of the control group, while mortality and severe disability rates were significantly lower than that of the control group （ all P 〈0.05）. Conclusion For patients with traumatic brain injury, ganglioside combined with hyperbaric oxygen therapy has better clinical outcomes, and can reduce the incidence of mortality and severe disability rate, and it is worthy of clinical application and promotion.

关 键 词：颅脑外伤 神经节苷酯 高压氧 

分 类 号：R651.15[医药卫生—外科学]