颈动脉粥样斑块及内中膜厚度与冠心病的关系  

Relationship between Both Carotid Atherosclerotic Plaque and the Intimia-Media Thickness with Coronary Artery Disease

作　　者：周慧青[1] 孙宁玲[1] 杨松娜[1] 王伟民[1] 刘美贞 胡恒慧[1] 

机构地区：[1]北京医科大学人民医院心内科,北京100044

出　　处：《高血压杂志》2000年第4期287-288,共2页Chinese Journal of Hypertension

摘　　要：目的 :探讨颈动脉内中膜厚度 (IMT)以及粥样斑块发生率情况与冠心病的关系。方法 :采用冠状动脉造影术筛选冠心病及非冠心病组 ,对 114例经选择性冠状动脉造影检查的患者行颈动脉超声检查 ,测量IMT以及观察粥样斑块发生率情况。结果 :对照组及冠心病组IMT为 0 6 7± 0 10mm及 0 85±0 2 6mm ,斑块发生率为 10 % (4 /4 0 )及 6 3.5 % (4 7/74) ,组间相比均具有显著性差异 ,P <0 0 0 1,以IMT≥ 0 85mm及 /或出现粥样斑块来预测冠心病 ,特异性 85 % ,敏感性 71.6 % ,阳性预测率 89.8%。结论 :颈动脉与冠状动脉粥样硬化间存在着密切关系 。Objective:To study the relationship between carotid artery intimia media thickness(IMT),atherosclerotic plaques,and coronary artery disease. Methods:Coronary artery ultrasonic examination was performed in 114 patients who had been consecutively examined by coronary artery angiography. Results:We found the IMT in control group and coronary artery disease group were 0 67±0 10 mm and 0 85±0 26 mm.,the prevanlence rate of atherosclerotic plaques were 10%(4/40)and 63.5%(47/74).There were significant differences between the two groups,P<0 001. An IMT≥0 85 mm and/or the occurrence of atherosclerotic plaques could predict the presence of coronary artery disease with a specifity of 85%, a sensitivity of 71.6% and a positive predictive value of 89.8%. Conclution:There were close relationship between carotid and coronary artery atherosclerosis. Carotid ultrasounic examination could help to predict the presence of coronary artery disease.

关 键 词：颈动脉 冠状动脉粥样硬化 冠心病 诊断 

分 类 号：R541.4[医药卫生—心血管疾病]