人参与当归配伍对人参总皂苷溶出率的影响  

Influences of the Dissolution Rate of Total Ginsenosides in Panax ginseng Concerted with Angelica sinensis

作　　者：贝圆[1] 冯俭[1] 罗方利[1] 席小兰[1] 谢玉[1] 李树翠[1] 

机构地区：[1]成都中医药大学,成都611137

出　　处：《中国实验方剂学杂志》2013年第23期129-131,共3页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：2010年成都市科技局科技攻关计划项目(10GGYB370SW-023)

摘　　要：目的:研究药对人参-当归中不同比例配伍后醇提液中人参总皂苷溶出率的变化,探讨两药配伍使用的作用机制,体现中药复方用药整体性理论。方法:采用紫外分光光度法对人参与当归不同比例配伍后醇提液中人参总皂苷含量进行测定。结果:人参与当归配伍后人参总皂苷的溶出率降低,不同配伍比例降低程度有所不同,1∶1配伍时人参总皂苷的降低率最高。结论:人参、当归配伍后人参总皂苷溶出率变化的研究,为药对人参-当归的配伍使用提供科学依据。Objective： To research the dissolution rate of the total ginsenoside of Panax ginseng and A. sinensis in different proportion after alcohol decocting,and discuss the compatibility mechanism of action and reflect the integrity theory of TCM. Method： The content of total ginsenoside in the alcohol extracts of P. ginseng and A. sinensis in different proportion was measured by the method of UV. Result： The content of total ginsenoside has degraded after P. ginseng and A. sinensis compatibility of different proportion in alcohol decocting. The different degrees varied from different proportions,1：1 proportion resulting in the highest reducing rate. Conclusion： The change of total ginsenoside after compatibility of different proportion of P. ginseng and A. sinensis can provide the scientific basis of the two drugs for compatibility use.

关 键 词：人参 当归 人参总皂苷 紫外分光光度法 

分 类 号：R284.1[医药卫生—中药学]