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机构地区:[1]北京首儿李桥儿童医院,北京101304 [2]首都儿科研究所附属儿童医院,北京100020
出 处:《中国实验方剂学杂志》2013年第23期291-294,共4页Chinese Journal of Experimental Traditional Medical Formulae
摘 要:目的:观察复方蓼大青叶口服液治疗儿童急性上呼吸道感染的疗效及安全性。方法:将123例急性上呼吸道感染患儿随机按数字法分为治疗组62例和对照组61例。两组在常规治疗基础上,治疗组采用复方蓼大青叶口服液治疗,对照组采用利巴韦林喷雾剂治疗。结果:①治疗组平均退热时间(2.8±1.2)d短于对照组(3.9±1.1)d,P<0.01;治疗组退热起效时间(2.1±1.0)d短于对照组(2.9±1.2)d,P<0.01。②体温疗效观察,治疗组总有效率93.5%,对照组总有效率85.2%,咽痛疗效观察,治疗组总有效率95.2%,对照组总有效率为80.3%,P<0.05。③治疗7 d后两组患儿其伴随症状比较,治疗组咳嗽、流涕、鼻塞等症状有效率均多于对照组,P<0.05。结论:复方蓼大青叶口服液治疗儿童急性上呼吸道感染热证具有起效快、疗效好,安全无毒副作用的特点,故可作为治疗儿童急性上呼吸道感染热证的首选药物之一。Objective: To observe the curative effect of the Compound Indigoplant oral liquid Solution on children acute upper respiratory infection and evaluate its safety. Method: One hundred and twenty-three children with acute upper respiratory infection were divided into two groups randomly,i e,the treatment group (62 cases,treated with the Compound Indigoplant oral liquid) and control group (61 cases,treated with Ribavirin Spray). Both groups were under conventional therapy. Result: ① The pyretolysis time of treatment group was shorter than control group,(2.8±1.2) d shorter than the control group (3.9±1.1) d,P〈0.01.The onset time on pyretolysis of treatment group was earlier than control group,(2.1±1.0) d shorter than the control group (2.9±1.2)d,P〈0.01.② The total effective rate on pyretolysis of treatment group 93.5% was higher than control group 85.2%. The total effective rate on pharyngalgia of treatment group 95.2% was higher than control group 80.3%,P〈0.05. ③ After treatment for 7 d,the effective rates on symptoms such as cough,nose running and nasal obstruction of treatment group were higher than control group, P〈0.05. Conclusion: The Compound Indigoplant oral liquid Solution has rapid onset and high efficacy in treating children with acute upper respiratory infection. Being safe and without any significant side effect,it can be regarded as one of the first choice drugs for children acute upper respiratory infection and has extensive application prospects.
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