基于化学动力学原理探讨健脑益智胶囊的吸湿性  

Investigation of Hygroscopic Capacity of Jiannaoyizhi Capsules with Chemical Kinetic Principles

作　　者：柳小莉 赵晓平[2] 范小璇[2] 王静楠[1] 郭东艳[1] 

机构地区：[1]陕西中医学院药学院,咸阳712046 [2]陕西中医学院附属医院,咸阳712000

出　　处：《医学研究杂志》2013年第11期78-79,共2页Journal of Medical Research

基　　金：陕西省科技厅基金资助项目(2011KTCL03-02)

摘　　要：目的应用化学动力学原理探讨健脑益智胶囊内容物的吸湿特性。方法采用过饱和法,得出健脑益智胶囊内容物的吸湿率,应用SPSS统计软件对健脑益智胶囊内容物的吸湿率进行数学模型拟合。结果健脑益智胶囊内容物吸湿特性曲线对二项式方程模型有较好的适应性,其临界相对湿度是65%。结论健脑益智胶囊在生产及贮存过程中应控制环境的相对湿度在65%以下,以保证制剂的稳定性。Objective To investigate the hygroscopic capacity of contents of JianNaoYiZhi Capsules, and chemical kinetic principles was used. Methods The hygroscopicity for the contents of Jiannaoyizhi capsules was obtained by supersaturated solution method, then SPSS statistical software was used to conduct mathematical regression for the hygroscopicity. Results The binomial equation had better a- daptability for the hygroscopic capacity curve of contents of Jiannaoyizhi capsules and the critical relative humidity was 65%. Conclusion During the production and storage of Jiannaoyizhi capsules, the relative humidity of environment should control under 65% to guarantee the preparation stability.

关 键 词：吸湿性 动力学模型 健脑益智胶囊 临界相对湿度 

分 类 号：R277.733.3[医药卫生—中医学]