支原体肺炎患儿血、尿胱抑素C检测的临床研究  

Clinical Study of Serum and Urine Cystatin C in Children with Mycoplasma Pneumonia

作　　者：陈正徐[1] 李曼[1] 王秀丽[2] 饶晓红[2] 

机构地区：[1]安徽省合肥市第二人民医院检验科,230011 [2]安徽省合肥市第二人民医院儿科,230011

出　　处：《中华全科医学》2013年第12期1949-1950,共2页Chinese Journal of General Practice

基　　金：合肥市科技局课题(合科[2011]25号)

摘　　要：目的探讨支原体肺炎患儿急性期、恢复期血、尿胱抑素C(Cys C)水平及其临床价值。方法支原体肺炎患儿36例,正常对照组120例,分别检测支原体肺炎患儿急性期、恢复期的血、尿胱抑素C、α1-微球蛋白、微量白蛋白、肌酐等指标,并对结果进行统计分析。结果与对照组相比,支原体肺炎患儿急性期血、尿Cys C含量差异均有统计学意义(P<0.01),而恢复期差异无统计学意义(P>0.05);支原体肺炎患儿急性期与恢复期比较,差异有统计学意义(P<0.05)。结论支原体肺炎患儿急性期肾功能有程度不等的损害,但肾功能损伤是可恢复的;血、尿Cys C测定对支原体肺炎患儿早期肾功能损害的诊断具有重要的临床价值。Objective To explore the levers of serum and urine cystatin C （ Cys C） in the acute and recovery phase of infants with mycoplasma pneumonia. Methods The serum and urine cystatin C, α1-microglobutin（ α1-MG）, microalbumin（ MA）, creatinine and other indicators were detected and analyzed in 120 healthy children（ control group） and 36 infants with mycoplasma pneumonia （ observation group）. Results The level of serum and urine Cys C in patients at acute phase was significantly different form the control group and patients at recovery phase（P 〈 0.01 ,P 〈 0.05 ）. There was no obvious difference between the control and recovery phase（P 〉 0.05 ）. Conclusion The injured renal functions in infants with mycoplasma pneumonia at acute phase were recoverable. The detection of serum and urine Cys C levels is helpful for the clinical diagnosis of the early renal function impairment infants with mycoplasma pneumonia.

关 键 词：胱抑素C 支原体肺炎 Α1-微球蛋白 微量白蛋白 

分 类 号：R563.13[医药卫生—呼吸系统] R446.5[医药卫生—内科学]