北京某地区HIV抗体筛查阳性情况和确证结果分析  

Analysis of positive screening and confirmed test for HIV antibody in some area of Beijing

作　　者：朱立国[1,2] 庄远[1] 王海宝[1] 席朝运[1] 魏超[1] 姜蕾[3] 汪德清[1] 

机构地区：[1]解放军总医院输血科,北京100853 [2]南开大学医学院,天津300071 [3]中日友好医院输血科,北京100029

出　　处：《中国卫生检验杂志》2013年第15期3101-3103,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的分析北京某地区ELISA检测HIV抗体阳性情况与免疫印迹试验（WB）结果，了解北京市该地区的HIV流行特征和规律，探索筛查阳性与确证试验结果的关系。方法对2005年-2012年北京地区无偿献血人群中HIV抗体阳性者的资料进行流行病学分析，并与确证试验结果比较。结果在165566名无偿献血人群中，HIV抗体筛查阳性的有375例，阳性率为0．23％，男女比例为6：1，18-25年龄段比例最大。经WB确证后，HIV阳性21例（占5．6％）、阴性307例（占81．87％）、不确定47例（占12．53％）。不确定的样本中，P24条带出现的几率最高，达到70．7％，其余都在20％以下。结论北京地区的HIV抗体筛查阳性率逐年升高，并呈现年轻化态势。WB确证方法仍存在不足，需辅助检测。Objective To study the relationship between anti - HIV detection by ELISA and confirmed test by Western blot and understand the epidemic features and regularity of HIV in this area. Methods The data of anti - HIV detection and WB confirmed test in volunteer blood donors from 2005 to 2012 in this area were analyzed retrospectively. Results A total of 375 samples were detected positive for HIV antibody in 165566 volunteer blood donors, the positive rate was 0.23%, the ratio of males and females was 6： 1, the positive rate was highest in population between 18 and 25 years old. After confirmed test, 21 cases were confirmed positive, 307 cases were confirmed negative, and 47 cases were unconfirmed. In unconfirmed samples, the appearance rate of p24 was highest （70.7%） and others were below 20%. Conclusion The positive rate of HIV shows a increase trend and tends to be younger. Supplementary test is need to deal with the limitations of WB confirmed test.

关 键 词：HIV抗体 血液筛查 免疫印迹试验 

分 类 号：R512.91[医药卫生—内科学]