2012年甘肃省大肠埃希菌的分布及耐药率分析  

Analysis of the distribution and drug resistance of Escherichia coli in Gansu province in 2012

作　　者：梁勤[1] 乔登嫣[1] 

机构地区：[1]甘肃省中医院检验科,甘肃兰州730050

出　　处：《中国卫生检验杂志》2013年第16期3296-3297,共2页Chinese Journal of Health Laboratory Technology

基　　金：甘肃省自然科学研究基金项目(0710RJZA007)

摘　　要：目的本文旨在了解甘肃省2012年大肠埃希菌在临床送检标本中的分布及对常见抗生素的耐药率,为社区及医院临床经验用药提供依据。方法统计分析2012年本省上报卫生部全国细菌耐药监测系统(Mohnarin网)中的相关数据,该系统基于WHONET 5.5分析软件。结果甘肃省大肠埃希菌菌株主要分离自痰液,尿液及分泌物。耐药率超过50%的药物有庆大霉素、氨苄西林、头孢唑啉、头孢曲松、头孢噻肟、环丙沙星、左旋氧氟沙星、头孢哌酮、四环素。结论关注并了解了本地区大肠埃希菌的分布及耐药率,正确指导临床经验性治疗感染性疾病。Objective To investigate the distribution of Escherichia coli in clinical specimens and the resistance to commonly used antibiotics in Gansu province in 2012, so as to provide basis for clinical empirical use of drugs in community and hospital. Methods The relevant data from national antimicrobial resistance monitoring system （Mohnarin net） about Gansu province were analyzed by WHONET 5.5 software. Results Escherichia coli strains were mainly isolated from sputum, urine and secre- tion in Gansu province. E. coli showed the drug resistance rate more than 50% to gentamicin, ampicillin, cefazolin, ceftriax- one, cefotaxime, ciprofloxacin, levofloxacin and cefoperazone. Conclusion Concern and understanding of the distribution and resistance of E. coli in the region can contribute to guide the clinical empirical treatment of infectious diseases correctly.

关 键 词：甘肃省 大肠埃希茵 分布 耐药率 

分 类 号：R378.21[医药卫生—病原生物学]