产复康泰胶囊的质量标准研究  

Study on Quality Standard of Chanfu Kangtai Capsules

作　　者：陈国珍[1] 黄慧[1] 刘睿[1] 

机构地区：[1]惠州市中医医院,广东惠州516001

出　　处：《中国药房》2013年第47期4477-4479,共3页China Pharmacy

摘　　要：目的：建立产复康泰胶囊的质量标准。方法：采用薄层色谱（TLC）法对产复康泰胶囊中当归、党参进行定性鉴别；以葡萄糖为参照，利用紫外分光光度法对产复康泰胶囊中的总多糖进行含量测定。结果：TLC特征明显、分离度好、斑点清晰，阴性对照无干扰。葡萄糖的质量浓度在0．001-0．050mg／ml范围内与吸光度呈良好的线性关系（r=0．9993）；精密度、稳定性、重复性试验的RSD〈3％；平均加样回收率为97．92％，RSD=2．87％（n=6）。结论：所建标准可用于产复康泰胶囊的质量控制。OBJECTIVE： To establish a quality standard for Chanfu kangtai capsules. METHODS： The qualitative identification of Angelica sinensis and Codonopsis Radix in Chanfu kangtai capsules was carried out by TLC. The contents of total polysaccharide were determined by UV spectrometry with glucose as a reference. RESULTS： TLC spots were clear and well-separated without the interference from blank control. The linear range of glucose was 0.001-0.050 mg/ml（r=0.999 3）; RSD of precision, stability and reproducibility tests were all lower than 3%; average recovery was 97.92% （RSD=2.87% ,n=6）. CONCLUSIONS：Established standard can be used for the quality control of Chanfu kangtai capsules.

关 键 词：产复康泰胶囊 薄层色谱法 紫外分光光度法 质量标准 当归 党参 总多糖 

分 类 号：R283.65[医药卫生—中药学] R917[医药卫生—中医学]