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作 者:金碧华[1] 朱若云[1] 彭剑涛[1] 申屠敏[1]
机构地区:[1]上海第二医科大学附属新华医院妇产科,上海200092
出 处:《中国优生优育(1990-2002上半年)》2000年第4期145-148,共4页Journal of Improving Birth Outcome and Child Development of China
摘 要:目的 研究妊娠期糖尿病饮食控制早晚与母婴预后。方法 根据饮食控制的早晚分孕24~28周早治组,孕妇48例;孕33周后晚治组,孕妇35例。回顾性总结妊娠期糖尿病母儿的预后。结果 妊高征、孕产期感染的发生率,晚治组分别为22.85%(8/35)和25.71%(9/35),与早治组2者均为6.25%(3/48)比较,差异有显著性(P<0.05)。新生儿高胆红素血症患病率晚治组为11.42%(4/35),与早治组0比较,差异有显著性(P<0.05)。妊娠期糖尿病组围产儿死亡率和畸形儿发生率分别为4.82%(4/83)和7.23%(6/83),与非糖尿病组0.44%(29/6 564)和0.23%(15/6 564),糖尿病晚治组5.71%(2/35)和14.29%(5/35)与早治疗组4.17%(2/48)和2.08%(1/48)比较,差异有显著性(P<0.01)。结论 24孕周时诊断、治疗妊娠期糖尿病十分必要。Objective To study the different outcome of mothers and their babies between early and late diet therapy of gestational diabetes mellitus (GDM). Methods The outcome of mothers and their babies was reviewed respectively in 83 pregnancy women with GDM. According to different duration of diet therapy, 48 cases whose gestation were less than 33 weeks were enrolled in early group, the rest of 35 cases in late group. Results There were incidences of 22. 85 (8/35) PIH and 25. 71 % (9/35) infection of the mothers during the period of pregnancy and postpartum in latc group. Compared with the incidences of 6. 25 % (3/48) PIH and 6. 25 % ( 3/48) infection in early group, it was significant (P<0. 05). About the incidence of newborn morbidity, it was higher in late group, especially the rate of highbilirubinemia reached 11.42 % (4/35). Compared with early group, it was significant statistically (P<0. 05). There was 4. 82 % (4/83) and 7.23 % (6/83) perinatal mortality and deformity in women with GDM than that in non-GDM 0.44 % (29/6 564) and 0.23 % (15/6 564),the late group 5. 71 % (2/35) and 14.29 % (5/35) compared with the early group 4. 17 % (2/48) and 2. 08 % (1/48), it was very significant respectively (P<0. 01). Conclusion To improve the outcome in GDM group, screening., diagnosis near 24 weeks gestation and early diet program are very important.
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