2型糖尿病合并低钠血症对胰岛素敏感性影响的研究  

The Study of Influence of Type 2 Diabetes with Hyponatremia on Insulin Sensitivity

作　　者：姜虹[1] 施康平[1] 

机构地区：[1]北京市第六医院内科,北京100007

出　　处：《中国医药导刊》2013年第11期1774-1774,1776,共2页Chinese Journal of Medicinal Guide

摘　　要：目的:研究探讨2型糖尿病合并低钠血症对胰岛素敏感性的影响。方法:48例存在低钠血症的2型糖尿病患者,在低钠血症期和低血症纠正后,对其血Na+、血管紧张素(ANGⅡ)、醛固酮(ALD)、肾素(PRA)和胰岛素敏感度进行测定,将其结果进行比较分析。结果:48例2型糖尿病合并低钠血症患者在低钠血症得到纠正后其血管紧张素(ANGⅡ)、醛固酮(ALD)和肾素(PRA)的测定值明显低于患者在低钠血症未纠正前的测定值,患者对胰岛素的敏感性升高。结论:合并低钠血症能降低2型糖尿病患者对胰岛素的敏感性,从而影响了2型糖尿病患者的治疗效果。Objective：Investigated the influence of type 2 diabetes with hyponatremia on insulin sensitivity of patients. Methods：Selected 48 cases with type 2 dabetes with hyponatremia. In hyponatremia and hyponatremia after correction, the level of Na, ANGⅡ, ALD, PRA, insulin sensitivity were detected,which of result were compared. Results： Patients with hyponatremia were corrected in hyponatremia in patients with type 2 diabetes mellitus,the level of Na, ANGⅡ, ALD, PRA in type 2 diabete patients with hyponatremia were lower than in type 2 diabete patients,the insulin sensitivity of were increased. Conclusion： Combined with hyponatremia could decline the insulin sensitivity of type 2 diabetes, and which was bad effects on treatment effective.

关 键 词：低钠血症 2型糖尿病 胰岛素敏感性 

分 类 号：R587.1[医药卫生—内分泌]