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出 处:《中国热带医学》2013年第10期1242-1244,共3页China Tropical Medicine
摘 要:目的了解天河口岸2010~2012年出入境人群流感流行特征,为科学防控疫情及进一步开展疫情预测预警提供依据。方法对2010~2012年天河口岸有流感样症状的出入境人员采鼻咽拭子,提取病毒RNA,采用荧光RT-PCR方法检测季节性甲型流感、乙型流感病毒核酸;同时进行流行病学个案调查。结果共采集鼻咽拭子1074份,其中流感病毒核酸阳性219份,总阳性率20.4%,各年度阳性率无差异。季节性H3型流感阳性96例,占43.8%,甲型H1N1流感阳性54例,占24.7%,乙型流感阳性69例,占31.5%,各年度流行优势株不同。总体男性样本阳性率18.8%(118/627),女性样本阳性率22.6%(101/447),阳性率无性别差异;0~5岁年龄组阳性率最低,为9.9%,与其他年龄组有显著差异;大陆居民样本阳性率21.9%(152/693),港澳台样本阳性率15.4%(27/175),其他国家样本阳性率19.4%(40/206),阳性率无差异。总体冬(12~2月)、春(3~5月)季阳性率最高,分别为27.6%和25.1%。结论 2010~2012年,天河口岸流感流行强度处于正常水平,各年度阳性率无差异;流行毒株为甲型H1N1流感、季节性H3型流感及B型流感病毒,各年度的流行优势株不同;流感季节性高峰在冬春季,峰值出现在1~3月和5~7月,呈双峰型或单峰型。Abstract:Objective To understand the epidemiologic characteristics of influenza at Tianhe port from 2010 to 2012. Methods Nasopharyngeal swabs from patients with symptoms of influenza-like illness were collected from 2010 to 2012 at Tianhe port. Influenza virus was detected by real time PCR. Results In total of 1 074 swabs,219 eases were positive, with a positive rate of 20.39%. Ninety-six eases were infected with season A H3 viruses (43.83%),54 eases with influenza H1N1 viruses (24.66%) and 69 eases with influenza B viruses (31.51%),the positive rate of influenza virus was highest, respectively 27.63% and 25.08% in Winter (December to February) and spring (March to May). Conclusions the influenza epidemic status were at the normal level at Tianhe port during the period of 2010-2012,no difference in influenza positive rate of annual. Epidemic strains were influenza H1N1 viruses,seasonal A H3 virus and influenza B virus,the predominant strain was different each year,The season peak of influenza epidemic was in winter and spring,as s single peak or double.
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