磁共振灌注检查在老年颈动脉狭窄患者支架置入术中的应用  

Application of magnetic resonance perfusion-weighted imaging in elderly carotid artery stenosis patients undergoing stenting

作　　者：杜志华[1] 李宝民[2] 王君[2] 李大胜[1] 于逢春[1] 陈新平[1] 杨兴东[1] 

机构地区：[1]北京市海淀医院神经内科,100086 [2]解放军总医院神经外科

出　　处：《中华老年心脑血管病杂志》2013年第12期1261-1264,共4页Chinese Journal of Geriatric Heart,Brain and Vessel Diseases

摘　　要：目的探讨磁共振灌注加权成像(perfusion-weighted imaging,PWI)检查在老年颈动脉狭窄患者支架置入术(carotid artery stenting,CAS)中的应用。方法选择15例年龄≥70岁的症状性颈动脉狭窄患者行CAS,在术前及术后72h分别行PWI检查,对比手术前后影像的改变,并与相关CT灌注成像研究结果进行对比。结果 15例患者全部成功实行CAS,术前PWI异常的患者在术后均有不同程度的改变,差异有统计学意义(P<0.01);术前PWI正常的患者在术后无变化。手术前后脑血流循环时间比较,差异有统计学意义(P<0.01)。结论 PWI检查在症状性颈动脉狭窄患者CAS前后有明显改变,其结果与相关CT灌注研究相符。Objective To study the application of magnetic resonance perfusion-weighted imaging （PWI） in elderly carotid artery stenosi （CAS） patients underging stenting. Methods Fifteen symptomatic CAS patients with their age ≥70 years were included in this study. Their PWI data before and 72 h after stenting were compared with their CT perfusion imaging data. Results The stenting was successful in the patients. The cerebral perfusion was better in the patients with ab- normal PWI after stenting than before stenting （P〈0.01） with no change in the patients with normal PWI before and after stenting. The cerebral circulation time was significantly shorter after stenting than before stenting （P〈0.01）. Conclusion The cerebral perfusion detected by PWI is significantly better in the patients after stenting than before stenting, which is consistent with that detected by CT perfusion imaging.

关 键 词：磁共振成像 颈动脉狭窄 支架 手术中并发症 再灌注损伤 

分 类 号：R445.2[医药卫生—影像医学与核医学] R743[医药卫生—诊断学]