机构地区:[1]中国疾病预防控制中心结核病预防控制中心统计监测部,北京102206 [2]中国疾病预防控制中心结核病预防控制中心主任办公室,北京102206 [3]中国疾病预防控制中心结核病预防控制中心患者关怀部,北京102206
出 处:《中国防痨杂志》2013年第11期905-909,共5页Chinese Journal of Antituberculosis
摘 要:目的分析全国Mtb与HIV双重感染防治工作重点县(区)对结核病患者进行HIV检测的结果,为进一步完善Mtb与HIV双重感染的检出策略提供依据。方法采用流行病学研究方法,分析2010年和2012年全国294个Mtb与HIV双重感染防治工作重点县(区)中开展HIV抗体检测的48 848和98 739例新登记结核病患者的筛查情况,同时将HIV抗体检测阳性率与全国结核病患者中HIV感染现状调查的阳性率及2540个非重点县(区)新登记结核病患者的HIV抗体检测阳性率进行对比。结果2010年,294个Mtb与HIV双重感染防治工作重点县(区)结核病患者平均HIV筛查率为43.32%(48 848/112 757);进行HIV检测的结核病患者中HIV的总体检出率为2.71%(1324/48 848);非重点县(区)进行HIV检测的结核病患者中HIV的总体检出率为0.41%(185/45 274)。2012年,相应的比率分别为86.63%(98 739/113 978)、1.63%(1605/98 739)和0.39%(628/159 586)。2010、2012年重点县(区)HIV检出率[2.71%(1324/48 848)、1.63%(1605/98 739)]与非重点县(区)HIV检出率[0.41%(185/45 274)、0.39%(628/159 586)]比较,差异均有统计学意义(χ2=789.17、1080.37;P值均<0.0001)。2010、2012年294个重点县(区)共检测出Mtb与HIV双重感染者分别为1324例和1605例,占全国估算患者例数的50.40%(1324/2627)和63.64%(1605/2522)。结论2012年全国Mtb与HIV双重感染防治重点县(区)新登记的结核病患者中HIV检测例数和检出的Mtb与HIV双重感染者与2010年相比均有显著上升,Mtb与HIV双重感染防治重点县(区)筛查策略实施效果良好。Objective To analyze the results of HIV screening among tuberculosis (TB) patients in national key counties (districts) for Mtb/HIV co-infection control and prevention, and to provide evidence for improving HIV screening strategy among TB patients. Methods The results of 48 848/98 739 screened patients of 294 national Mtb/HIV co-infection key counties (districts) in 2010/2012 were analyzed, and the positive rate was compared with that of National HIV Infection Survey among TB patients and of 2540 non-priority counties. Results In 2010, the average HIV screening rate in 294 key counties (districts) was 43.32% (48 848/112 757), the overall HIV detection rate in key counties and non-priority counties were 2.71% (1324/48 848) and 0.41% (185/45 274) respectively, and the corresponding rates were 86.63% (98 739/113 978), 1.63% (1605/98 739) and 0.39% (628/159 586) in 2012. The HIV detection rates of key counties were 2.71% (1324/48 848) and 1.63% (1605/98 739) respectively in 2010 and 2012, while those of non-priority counties were 0.41% (185/45 274) and 0.39% (628/159 586). The differences of HIV detecting rate were significant between key counties and non-priority counties in 2010 and 2012 (χ2=789.17/1080.37, P〈0.0001). The numbers of Mtb/HIV co-infection cases detected in 294 key counties in 2010 and 2012 were 1324 and 1605 respectively, which accounted for 50.40% (1324/2627) and 63.64% (1605/2522) of the estimated number of national Mtb/HIV patients. Conclusion The number of screened cases and Mtb/HIV patients detected in key counties in 2012 has increased significantly than in 2010, and the implementation effect of the strategy of HIV screening among TB patients in Mtb/HIV co-infection key counties is good.
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