一起食源性停乳链球菌类马亚型暴发感染调查  

Infection with food-contaminated streptococcus dysgalactiae subspecies equisimilis during its outbreak

作　　者：翟永志[1] 刘梦林[1] 张志强[1] 陈歆[1] 刘昕[1] 田琳[1] 肖红菊[1] 刘刚[1] 

机构地区：[1]解放军总医院发热疾病科,北京100853

出　　处：《解放军医学院学报》2013年第11期1135-1137,共3页Academic Journal of Chinese PLA Medical School

基　　金：国家科技重大专项（2013ZX1004805-003）;解放军总医院临床科研扶持基金（2012FC-TSYS-3033）

摘　　要：目的调查一起食源性停乳链球菌类马亚型(streptococcus dysgalactiae subspecies equisimilis,SDSE)暴发感染,为快速诊治SDSE感染暴发积累经验。方法采集和分析驻京某部队2012年9月30日-10月1日暴发呼吸道感染70例患者的流行病学资料、症状、体征,对比治疗前后实验室检查结果,进行流行病学和统计学分析。结果 70例患者中,表现为发热66例(94.29%),咽痛62例(88.57%)、扁桃体化脓36例(51.43%)。其中38例(54.29%)咽拭子病原学培养结果为SDSE。患者治疗前后,白细胞计数(white blood cell count,WBC)、中性粒细胞比例(neutropenia leukocyte percent,N%)、C-反应蛋白(C-reactive protein,CRP)、白细胞介素-6(interleukin-6,IL-6)水平差异有统计学意义(P<0.01),降钙素原(procalcitonin,PCT)阳性率差异无统计学意义(P>0.05)。结论食源性SDSE致人群呼吸道暴发感染比较罕见,病原学分离鉴定是关键,血常规和IL-6检测是较好的辅助检查和病情监测方法。Objective To accumulate experience with the rapid diagnosis of infection with food-contaminated streptococcus dysgalactiae subspecies equisimilis （SDSE） during its outbreak. Methods Epidemiology data, symptoms, and signs of 70 patients with respiratory tract infection in a certain Chinese PLA unit stationed in Beijing during its outbreak from September 30, 2012 to October 1, 2012 were analyzed. Results Of the 70 patients, 66 （94.29%） were manifested as fever, 62 （88.57%） as sore throat, 36 （51.43%） as tonsillitis, and 38 （54.29%） were diagnosed with SDSE infection according to the cultured pharynx secretion. The number of white blood cells and neutrophils, the serum CRP and IL-6 levels were significantly lower after treatment than before treatment （P 〈 0.01）. However, no significant difference was found in serum procalcitonin level before and after treatment （P 〉 0.05）. Conclusion Respiratory tract infection with food-contaminated SDSE seldom occurs during its outbreak. Isolation and identification of SDSE are the key to its rapid diagnosis. Routine blood examination and serum IL-6 testing are the effective accessory examination and disease-monitoring methods.

关 键 词：停乳链球菌类马亚型 调查 暴发 C反应蛋白 白细胞介素-6 

分 类 号：R183.4[医药卫生—流行病学]