两种蒙山地衣植物化学成分研究  

Study on the Chemical Constituents of Two Lichen Plants from Meng Mountain

作　　者：张海娟[1,2] 朱德全[2,3] 孙丽彦[4] 葛朝晖[1] 许俊杰[1] 冯尚彩[1,2] 

机构地区：[1]临沂大学现代中药研究所,山东临沂276000 [2]山东省鲁南中药材资源开发工程技术研究中心,山东临沂276000 [3]临沂市人民医院,山东临沂276003 [4]泰山医学院药学院,山东泰安271000

出　　处：《中药材》2013年第9期1454-1456,共3页Journal of Chinese Medicinal Materials

基　　金：山东省科技发展计划资助项目(2012GNC11027)

摘　　要：目的:研究两种蒙山地衣植物梅衣(Parmelia tinctorum Despr.)和小裂芽梅衣(Parmelia nimandairana A.Z.)的化学成分。方法:利用硅胶柱层析、Sephadex LH-20凝胶柱层析和高效液相等色谱技术分离纯化化学成分,通过理化性质和波谱数据确证其结构。结果:从梅衣中分离得到4个化合物:茶渍衣酸(I)、去甲环萝酸(II)、苔黑酚羧酸乙酯(III)和苔黑酚(IV);从小裂芽梅衣中分得2个化合物:松萝酸(Ⅴ)和水杨嗪酸(Ⅵ)。结论:其中,化合物Ⅴ和Ⅵ为首次从小裂牙梅衣中分离得到。Objective ： To investigate the chemical constituents of the lichen plants Parmelia tinctorum and Parmelia nimandairana collected from Meng Mountain in Shandong province. Methods： Various chromatographic techniques were used to isolate and purify the constituents and their structures were elucidated by means of spectral evidence and physiochemical properties. Results ： Four compounds were isolated from Parmelia tinctorum and identified as： lecanoric acid （ I）, evernic acid （II） , ethyl orsellinate （III ） and 3,5-di- hydroxytoluene （IV）. Two compounds were isolated from Parmelia nimandairana and identified as： usnic acid （ V ）and salazinic acid （ VI ）. Conclusion ： Compounds V and VI are isolated from Parmelia nimandairana for the first time.

关 键 词：梅衣 小裂芽梅衣 化学成分 

分 类 号：R284.1[医药卫生—中药学] R284.2[医药卫生—中医学]