河南省健康人群百日咳、白喉、破伤风抗体水平分析  

作　　者：刘倩[1] 丰达星[1] 赵升[1] 于燕[1] 郭永豪[1] 封秀红[1] 张明瑜[1] 徐瑾[1] 

机构地区：[1]河南省疾病预防控制中心,河南450016

出　　处：《当代医学》2013年第31期160-161,共2页Contemporary Medicine

摘　　要：目的了解河南省健康人群百日咳、白喉、破伤风抗体水平,为制定DPT免疫策略提供依据。方法 2011-2012年度分4个年龄组在河南省5个县(区)抽取健康人共717名,采用间接ELISA法检测血清中百日咳、白喉、破伤风抗体水平。结果在检测的717名健康人中,百日咳IgG抗体平均阳性率为40.59%,白喉IgG抗体阳性率较高,达到82.29%,破伤风IgG抗体阳性率为75.73%。结论白喉和破伤风抗体水平较高,而百日咳抗体水平过低,提示河南省存在百日咳流行隐患,要重视百日咳疫苗接种工作,扩大接种覆盖率。Objective Analysis on Antibody Levels of DPT in healthy population in Henan, and to provide theoretic basis for the immunization strategy of DPT. Methods 717 healthy people in 5 counties in Henan province were divided into 4 groups by age, then serum separated to test antibody levels of DPT by ELISA. Results The antibody positive rate of diphtheria, pertussis and tetanus were 82.29%, 40.59% and 75,73% respectively. Conclusion The antibody levels of diphtheria and tetanus were higher than pertussis＇s. Vaccine immunization of pertussis should be focused on and the coverage of immunization should be extended.

关 键 词：百日咳 白喉 破伤风 抗体 

分 类 号：R186[医药卫生—流行病学]