子宫腺肌症痛经患者生存质量及影响因素分析  

Analysis of Quality of Life and Influencing Factors of Adenomyosis-Associated Dysmenorrhea

作　　者：杨舫[1] 时丽媛[1] 王清[1] 

机构地区：[1]中日友好医院,北京市朝阳区樱花园东街2号100029

出　　处：《中医杂志》2013年第22期1929-1932,共4页Journal of Traditional Chinese Medicine

基　　金：首都医学发展科研基金资助项目(SF-2009-Ⅲ-25)

摘　　要：目的评估子宫腺肌症痛经患者的生存质量及其影响因素。方法选择子宫腺肌症痛经患者130例作为病例组,并设同期社区健康同龄女性120例为对照组。采用横断面调查的方法,收集两组受试者一般资料及病例组患者的病程、痛经程度、中医证候积分、视觉模拟评分(VAS评分)、CA125、子宫大小等,采用健康调查简表(SF-36)中文版对两组受试者生存质量进行评估,并以多元逐步回归分析筛选子宫腺肌症痛经患者生存质量的影响因素。结果纳入统计的有效问卷共163份,其中病例组73份,对照组90份。与对照组相比,病例组SF-36量表中总体健康感、躯体角色功能、社会功能、机体疼痛评分及身体健康总分均相对偏低(P<0.01)。多元逐步回归分析显示,痛经积分、中医证候积分、VAS积分、CA125值及子宫大小与子宫腺肌症痛经患者生存质量均无显著相关性。年龄、病程及中医证候与子宫腺肌症痛经患者生存质量均未能建立合理的相关系数。结论子宫腺肌症痛经患者生存质量较健康人群普遍偏低,小样本研究未显示痛经积分、中医证候、VAS积分、CA125等指标与其生存质量的相关性。Objective To evaluate the quality of life（QOL）and its influencing factors in adenomyosis-associated dysmenorrhea patients.Methods Seventy-three adenomyosis-associated dysmenorrhea patients were chosen as the case group and 90healthy women at the same age were chosen as the control group.A cross-sectional survey method was used to collect the general information in both groups and the data on the course of disease,degree of dysmenorrhea,TCM pattern score,visual analog scale（VAS）score,CA125and uterine size in the case group.The QOL was evaluated according to the 36-item short form health survey（SF-36）.The factors influencing QOL was analyzed and screened with multiple stepwise regression analysis.Results Totally 163valid questionnaires were included,with 73and 90in the case group and control group respectively.Comparing with the control group,the scores of vitality,physical role function,social function,bodily pain and general health in the SF-36in the case group were significantly lower（P〈0.01）.The multiple stepwise regression analysis showed that there was no significant correlation between dysmenorrhea score,TCM pattern score,VAS score,CA125,uterine size and QOL.There was no reasonable correlation coefficient between QOL and age,duration and patterns.Conclusion The QOL in adenomyosis-associated dysmenorrhea patients is generally lower than that in the healthy persons.Small sample study cannot show correlation between dysmenorrhea score,TCM pattern score,VAS score,CA125and QOL.

关 键 词：子宫腺肌症 痛经 生存质量 SF-36 

分 类 号：R711.71[医药卫生—妇产科学]