基于临床医疗科研信息共享系统AECOPD证症相关性分析研究  

Correlation Analysis of Syndromes and Symptoms of TCM AECOPD Based on Clinical Research Information Sharing System

作　　者：胡金亮[1] 李素云[1] 余海滨[1] 张润顺[2] 周雪忠[3] 张兴红[1] 李真[1] 

机构地区：[1]河南中医学院第一附属医院,郑州450000 [2]中国中医科学研究院广安门医院,北京100053 [3]北京交通大学计算机与信息技术学院,北京100044

出　　处：《世界科学技术-中医药现代化》2013年第7期1596-1599,共4页Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology

基　　金：国家中医药管理局2012中医药行业科研专项(HY12079675):中医临床医疗科研信息共享系统的应用及推广研究;负责人:李真

摘　　要：目的：利用复杂网络开展慢性阻塞性肺疾病急性加重期（AECOPD）证症相关性分析研究，为AECOPD证候诊断标准的修订提供科学依据，并探索有关技术方法的推广应用。方法：利用当前我院临床医疗科研信息共享系统，开展大数据（2011年8月~2013年1月间3000份格式化电子病历数据）导入数据库，通过ETL软件进行数据处理，运用复杂网络进行数据挖掘。获取AECOPD常见证候常见症状的相关度MISCR值（证候与症状的相关性），并与现有标准对比分析。结果：痰热壅肺、肺肾气虚、痰浊阻肺等各证候对应的症状群与现有标准对应分析发现临床所见证候多虚症、实症夹杂，但个别症状与对应的证候相矛盾。结论：基于临床医疗科研信息共享系统，开展AECOPD证症相关性分析研究，为中医证候诊断标准的验证和修订提供有力的证据和方法学研究。This study was aimed to analyze correlation between traditional Chinese medicine （TCM） syndromes and symptoms of acute exacerbation chronic obstructive pulmonary disease （AECOPD） based on complex network in order to provide a scientific basis for TCM syndrome amendments of diagnostic criteria, and explore relevant technologies to promote its application. By way of the current Clinical Research Information Sharing System, data and data pro-cessing were carried out （EHR 3000 between August 2011 and January 2013） into the database by ETL software. The MISCR （correlation between common symptoms and common syndromes） from both common symptoms and com-mon syndromes of AECOPD was analyzed with existing diagnosis standards of AECOPD. The comparative analysis on TCM syndromes such as heat phlegm obstructing the lung, lung and kidney qi deficiency, phlegm turbid obstructing the lung and their correspondent existing diagnosis standards of AECOPD showed that the common TCM syndromes in the clinic are the mixture of deficiency and excess syndromes. However, some individual symptom is contradicted to its correspondent syndrome. It was concluded that based on the Clinical Research Information Sharing System, the research on correlation analysis between syndromes and symptoms of AECOPD can provide strong evidence and methodology for the validation and revision of TCM diagnostic criteria.

关 键 词：临床医疗科研信息共享系统 证候分布 证症相关性分析 复杂网络 

分 类 号：R241[医药卫生—中医诊断学]