右心室流出道间隔部起搏对完全性房室传导阻滞患者心功能的影响  被引量:2

Effects of right ventricular outflow septal pacing on cardiac functions in patients with complete atrioventricular block

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作  者:邵山[1] 王小青[1] 钱波[1] 孙建辉[1] 

机构地区:[1]常州市第一人民医院心内科,江苏常州213003

出  处:《心脏杂志》2013年第5期558-560,共3页Chinese Heart Journal

摘  要:目的:比较右心室流出道间隔部(RVS)起搏与右心室心尖部(RVA)起搏对左右心室间收缩同步性、左室重构及心功能的影响。方法:①入选Ⅲ度房室传导阻滞患者61(男39,女22)例,随机分入RVS部起搏组(RVS组,n=33)和RVA部起搏组(RVA组,n=28)。②比较两组患者植入术中及术后12月心室电极导线参数(起搏阈值、R波感知及阻抗)的差异。③观察两组患者术前及术后12月QRS波时限;术后应用组织多普勒同步图(TSI)分别测定两组左、右心室侧壁基底部收缩达峰时间差(△Ts)。评价心室间不同步的程度。④行多普勒超声心动图(UCG)检查,观察两组术前及术后12月左室舒张末期内径(LVEDD)及左室射血分数(LVEF)的变化,比较不同起搏部位对心功能的影响。结果:①两组患者测试的起搏阈值、R波感知及导线阻抗无统计学差异。②两组患者术后QRS波时限均较术前延长(均P<0.01),RVA组较RVS组延长更为明显(P<0.01)。RVS组与RVA组△Ts分别为(27±14)ms和(90±22)ms,有统计学差异(P<0.01)。③术后12个月两组LVEDD均较术前增加,RVA明显大于RVS组[(54±5)mm vs.(51±5)mm,P<0.05]。RVA组术后12月LVEDD较术前明显增加[(54±5)mm vs.(50±4)mm,P<0.05],术后12月两组LVEF均较术前降低[RVS组:(0.58±0.14)vs.(0.63±0.09),P<0.01;RVA组:(0.51±0.12)vs.(0.64±0.13),P<0.01],组间比差异不显著。结论:RVS起搏对心室间同步性、左室重构的影响要优于RVA起搏。AIM: To compare the effect of right ventricular outflow tract septum (RVS) pacing and right ventricular apical (RVA) pacing on contraction synehrony, ventricular remodeling and cardiac functions. METHODS: Sixty-one patients (39 males, 22 females ) with III atrium ventricular conduction block (AVB) were randomly divided into RVS group (n = 33) and RVA group (n = 28). The parameters of the pacing leads on implantation and post-implantation and changes of QRS duration of pre- and post-implantation were observed. The ventricular synehrony was evaluated by tissue Doppler and left ventricular end-diastolic diameter (LVEDD) and left ventricular ejection fraction (LVEF) were compared between groups. RESULTS: No statistical differences were observed in the pacing parameters between groups (P 〉 0.05 ). Post-implantation QRS duration was significantly prolonged in both groups (P 〈 0. 01 ), especially in the RVA group (P 〈0. 01). Ts (time to peak systolic velocity) of the left lateral wall to the right wall was (27 + 14) ms for RVS pacing and (90 _+22) ms for RVA pacing (P 〈0.01 ). LVEDD of post-implantation significantly increased compared with pre-implantation in RVA group I ( 54 _+ 5 ) mm vs. (50 _+ 4) mm, P 〈 0. 051. LVEF statistically decreased in both groups [ RVS : (0.58 _+ 0. 14)'vs. (0.63_+0.09), P〈0.01; RVA: (0.51_+0.12) vs. (0.64_+0.13), P〈0.01J. CONCLUSION:RVS pacing achieves a better effect on cardiac contraction synchrony and ventricular remodeling than RVA pacing.

关 键 词:右室流出道间隔部 右室心尖部 起搏 心功能 

分 类 号:R541.1[医药卫生—心血管疾病]

 

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