超声心动图在评价妊娠期糖尿病胎儿心功能中的作用  

Evaluation of fetal heart function by echocardiography in women with gestational diabetes

作　　者：何萍[1] 张玉奇[2] 徐惠英[1] 洪向丽[1] 郭丽丽[1] 

机构地区：[1]同济大学附属第一妇婴保健院超声科,上海200040 [2]上海交通大学医学院附属上海儿童医学中心,上海200127

出　　处：《同济大学学报（医学版）》2013年第5期54-60,共7页Journal of Tongji University(Medical Science)

基　　金：上海市科委项目(10DZ1951200);上海市卫生局青年科研基金(20114Y178)

摘　　要：目的应用超声心动图观察妊娠期糖尿痛(gestational diabetes mellitus,GDM)胎儿心脏构型及功能的变化,判断心脏构型与心功能变化间的关系。方法 73例GDM胎儿为研究对象,用二维超声、M型超声及脉冲多普勒超声测量胎儿室间隔舒张末期厚度(IVSd),左室射血分数(LVEF),二、三尖瓣E、A峰值速度比(E/A_(MV)、E/A_(TV))及心肌工作指教(MPI)等,并与正常妊娠组胎儿各指标进行对比。结果 30周后,GDM胎儿左、右心心肌工作指数(LV MPI、RV MPI)明显高于正常组(P<0.05)。结论 GDM胎儿心脏功能变化发生于孕30周后,心肌工作指数可以比较准确地反映胎儿心功能的变化。Objective To evaluate fetal heart function by echocardiography in women with gestational diabetes mellitus. Methods Seventy-three fetuses of mothers with gestational diabetes mellitus were included. Two-dimensional untrasonography, M-mode ultrasonography and Doppler echocardiography were performed. The interventricular septum thickness at end diastole （IVSd）, left ventricular ejection fraction（ LVEF）, ratio of E and A of mitral flow （E/AMy）, ratio of E and A of tricuspid flow （ E/ATv ） and myocardial performance index （MPI） of fetal heart were measured. These findings were compared with those of normal fetuses. Results The left and right ventricular MPIs of the diabetic group were significantly higher than those of control group after 30 weeks of gestation （P 〈0.05 ）. Conclusion Heart function changes are found in fetuses of mothers with gestational diabetes mellitus from 30 weeks of gestation.

关 键 词：超声心动图 妊娠期糖尿病 心功能 心肌工作指数 

分 类 号：R540[医药卫生—心血管疾病]