PCOS并发MS育龄妇女诱导排卵前行预处理的临床意义  

The clinical meaning of pre-treatment of childbearing age women with PCOS concurrent MS before ovulation induction

作　　者：邹琳[1] 李洪波[2] 韦冰[1] 许丽华[1] 

机构地区：[1]广东医学院附属医院生殖医学中心,广东湛江524001 [2]广东医学院附属医院检验科,广东湛江524001

出　　处：《中国优生与遗传杂志》2013年第11期103-104,共2页Chinese Journal of Birth Health & Heredity

摘　　要：目的探讨多囊卵巢综合征(PCOS)并发代谢综合征(MS)的育龄妇女在诱导排卵前予口服避孕药及比格列酮行预处理的临床意义。方法回顾性分析2010年1月至2012年12月于广东医学院附属医院生殖医学中心确诊PCOS的育龄妇女383例,均有排卵稀发或排卵障碍。分为对照组(无并发MS者,直接诱导排卵治疗)106例;观察组A(并发MS者,直接诱导排卵治疗)52例;观察组B(并发MS者,诱导排卵治疗前行预处理)225例。比较三组患者的优势卵泡个数、子宫内膜厚度及妊娠成功率。结果观察组B和对照组临床妊娠率均高于观察组A,差异有统计学意义(P<0.05);观察组B的临床妊娠与对照组相似,差异无统计学意义(P>0.05);三组患者诱导排卵的优势卵泡个数、子宫内膜厚度比较差异无统计学意义(P>0.05)。结论 PCOS并发MS育龄妇女诱导排卵前行预处理具有临床意义。Objective： To explore clinical significance of the pre - treatment taking oral contraceptives and pioglitazone in child bearing age women with polycystic ovary syndrome （PCOS） concurrent metabolic syndrome （MS） before ovulation induction. Meth- ods ： Go to a review and analysis of 383 iehildbearing age women confirmed PCOS, both ovulation thin hair or ovulation disorders, in Department of Reproductive Medicine of Affiliated Hospital of Guangdong Medical College from January 2010 to December 2012. Select 106 women received straightforward ovulation induction treatmentwith without concurrent MS （Control group） ; Select 52 women re- ceived straightforward ovulation induction treatmentwith with concurrent MS （Observation group A） ; Select 225 women received pre- treatment before ovulation induction with concurrent MS （Observation group B）. Results： The clinical pregnancy rate in observation group B and the control group was higher than that in observation group A. The change was statistically significant （ P 〈 0. 05 ）. The clinical pregnancy rate in observation group B is similar with that in control group. The difference was not significant （ P 〉 0. 05 ）. The difference was not statistically significant in the Number of dominant follicle ovulation induction and the endometrial thickness of three groups of patients （ P 〉 0. 05 ）. Conclusions ： The clinical significance was great in the pre - treatment of childbearing age women with PCOS concurrent MS before ovulation induction.

关 键 词：多囊卵巢综合征 代谢综合征 预处理 

分 类 号：R711.75[医药卫生—妇产科学]