Selective derivatization of oxime-blocked tolylene-2,4-diisocyanate  

作　　者：Yang Sang Peng-Fei Yang Tian-Duo Li 

机构地区：[1]Shandong Provincial Key Laboratory of Fine Chemicals, Shandong Polytechnic University

出　　处：《Chinese Chemical Letters》2013年第11期1019-1022,共4页中国化学快报（英文版）

基　　金：financially supported by the National Natural Science Foundation of China (Nos. 21176147, 21276149 and 21204044);Program for Scientifc Research Innovation Team in Colleges and Universities of Shandong Province

摘　　要：A selective reaction of cyclohexanone oxime-blocked tolylene-2,4-diisocyanate（2,4-TDI）with amino siloxane was observed,in which amines were capable of discriminating two reactive groups in the 2,4-TDI molecule.Thus,tolylene-2-tert-butyldimethylsilyloxyethyl carbamide-4-cyclohexanone oxime carbamate was synthesized and its precise structure was determined by single-crystal X-ray diffraction.Moreover,it was found that oxime-blocked isocyanate could react selectively with the–NH2group with the–OH group unprotected in ethanolamine.A selective reaction of cyclohexanone oxime-blocked tolylene-2,4-diisocyanate（2,4-TDI）with amino siloxane was observed,in which amines were capable of discriminating two reactive groups in the 2,4-TDI molecule.Thus,tolylene-2-tert-butyldimethylsilyloxyethyl carbamide-4-cyclohexanone oxime carbamate was synthesized and its precise structure was determined by single-crystal X-ray diffraction.Moreover,it was found that oxime-blocked isocyanate could react selectively with the–NH2group with the–OH group unprotected in ethanolamine.

关 键 词：Cyclohexanone oxime Tolylene-2 4-diisocyanate Ethanolamine Selective reactions 

分 类 号：O623.624[理学—有机化学]