First total synthesis of (±)-malaysianone A and (±)-tanariflavanones B  

作　　者：Jin-Hui Yang Bing-Bing Chen Yi-Min Xie Yao Feng Xiao-Qin Ma 

机构地区：[1]State Key Laboratory Cultivation Base of Natural Gas Conversion, Ningxia University

出　　处：《Chinese Chemical Letters》2013年第11期1027-1029,共3页中国化学快报（英文版）

基　　金：financially supported by the National Natural Science Foundation (Nos. 21162021, 20962016);the Program for New Century Excellent Talents in University (No. NCET-090860)

摘　　要：A concise approach for the frst total synthesis of two naturally occurring flavanoids,（）-malaysianone A（1）and（）-tanariflavanones B（2）,has been accomplished with total yields of 12.9%and 10.4%,respectively.The key steps were regioselective deprotection and regioselective synthesis of 5-formaldehyde-8-hydroxy-2-[40-methyl-30-penteneyl]-dihydro-1-benzopyran（8）.A concise approach for the frst total synthesis of two naturally occurring flavanoids,（）-malaysianone A（1）and（）-tanariflavanones B（2）,has been accomplished with total yields of 12.9%and 10.4%,respectively.The key steps were regioselective deprotection and regioselective synthesis of 5-formaldehyde-8-hydroxy-2-[40-methyl-30-penteneyl]-dihydro-1-benzopyran（8）.

关 键 词：Malaysianone A Tanariflavanones B Total synthesis Flavanoids 

分 类 号：O621.3[理学—有机化学]