新型持续皮肤牵张器促进皮肤创面愈合的实验研究  

Study of a Novel Skin Continual-Stretching Device for Enchancement of Skin Healing

作　　者：马志军[1] 毕龙[1] 杨涛[2] 陈博[1] 王晓东[2] 袁志[1] 

机构地区：[1]第四军医大学西京医院骨科,陕西西安710032 [2]武警天津市总队医院,天津300162

出　　处：《现代生物医学进展》2013年第29期5649-5652,共4页Progress in Modern Biomedicine

基　　金：国家自然科学基金青年基金项目(30901532)

摘　　要：目的:介绍自主研制的持续皮肤牵张器,探讨自主研制的持续皮肤牵张器治疗皮肤缺损的可行性和效果分析。方法:自主研制的持续皮肤牵张器8套;白色家猪6只,将每只猪的背部(两侧)切除矩形皮肤软组织缺损,形成12个创面,分为二组,实验组4只猪8个创面,对照组2只猪4个创面,创面均为10 cm×6 cm,实验组创面用自制持续皮肤牵张器行皮肤伸展术治疗,对照组创面自行愈合。结果:实验组与对照组每日创面缩小面积相差较多,差异有统计学意义,实验组皮肤缺损行5-6天皮肤伸展术治疗后,可直接行二期缝合关闭,对照组1周后仍存在较大皮肤缺损,无法缝合关闭。结论:应用自制持续皮肤牵张器行皮肤伸展术,可以早期快速闭合皮肤创面。自制持续皮肤牵张器克服了以往牵张器的不足,具有使用方便,效果可靠,并发症少等优点,有良好的应用前景。Objective： To introduce a continued skin stretching device by investigating the feasibility and effects on the treatment of skin defects. Methods： 8 sets of skin stretching device and six pigs were used in this study. Two back skin defects were prepared in each of the six pigs, and twelve skin defects model were gotten. All the defects were divided into two groups： eight defects in the experimental group and four in the controll group. The area of each defect was 10 cm × 6 cm. Inthe experimental group, the skin defects were treated by the skin stretching device. In the control group, the defects were leR by itself. Results： The area narrowed daily in the experimental group was larger than that of the control group with statistically significant differences. Five-six days later, the defects in the experimental group could be closed by the application of this continuous skin stretching device. And the skin wound could be sealed at the econdary stage. However, the defects in the control group could not be closed after one week. A big skin gap still could be found in the wound. Conclusion： This continuous skin stretching device can be used in the treatment of skin defect and help the closure of skin in early stage. The deficiencies of the previous skin stretching device could be overcome by this continuous skin stretching device. With its feasibility, the device can be easily used on the treatment of skin defects for better prospects.

关 键 词：皮肤伸展术 皮肤牵张器 皮肤缺损 

分 类 号：Q95-3[生物学—动物学] R62[医药卫生—整形外科]