传染性法氏囊病病毒变异E株对法氏囊上皮形态和机能的影响  

Effect of Infectious Bursal Disease Virus on the Morphology and Function of Epithelia of the Bursa of Fabricius

作　　者：陈明勇[1] 赵德明[1] 高齐瑜[1] 乔健[1] 

机构地区：[1]中国农业大学动物医学院,北京100094

出　　处：《华中农业大学学报》2000年第5期471-474,共4页Journal of Huazhong Agricultural University

摘　　要：运用传染性法氏囊病病毒变异E株通过泄殖腔人工感染SPF鸡胚和雏鸡 ,观察了法氏囊上皮细胞的形态学变化和机能变化。结果表明 ,病毒感染后 ,法氏囊上皮细胞微绒毛坏死、断裂、脱落 ,上皮细胞之间连接松散 ,表面上皮细胞坏死剥脱 ,形成火山口样特征性变化 ;The morphological and functional changes of the bursal epithelia of the chickens infected with IBDV VE were studied. The results showed that the microvilli of the bursal epithelium reduced in number and size. Loss of surface epithelium led to extensive surface erosion and exposure of the underlying lymphoid follicles. The function of endocytosis and secretion possessed by the bursal epithelium was apparently inhibited and damaged.\;

关 键 词：传染性法氏囊病病毒变异E株 鸡 免疫抑制 

分 类 号：S858.315.3[农业科学—临床兽医学] S852.35[农业科学—兽医学]