湖北土家族X-STR基因座多态性及法医学应用研究  

Application Research of Hubei Tujia X-STR Polymorphism and Forensic Science

作　　者：高绪辉 田业军 刘衡[3] 

机构地区：[1]恩施自治州公安局,恩施445000 [2]湖北省宣恩县公安局,宣恩445500 [3]湖北省咸丰县公安局,咸丰445600

出　　处：《中国公共安全（学术版）》2013年第4期104-107,共4页China Public Security(Academy Edition)

摘　　要：为了解湖北土家族人群X-STR基因座的多态性,本文探讨其在法医学上的应用价值,抽选了210人湖北土家族无关个体样本,采用PCR扩增和末端标记荧光循环测序的方法,分析其DXS6804、DXS7130、DXS7132和DXS8378 4个X-STR基因座的等位基因频率及基因型分布。结果表明:其中的五项法医学应用指标与其他民族及种族存在显著区别,差异有统计学意义(P<0.05)。这一研究结果证实湖北土家族群体中DXS6804、DXS7130、DXS7132和DXS8378 4个X-STR基因座具有较高遗传多态性,在法医学个体识别和亲权鉴定中有较高应用价值,同时也丰富了少数民族STR基因数据库。To understand the X-STR loci polymorphism ofHubei Tujia people, this paper explores its application value in forensic science. This paper selected 210 Hubei Tujia sample of unrelated individuals, using PCR amplification and end- labeled fluorescent cycle sequencing method to analyze the loci allele frequencies and genotype distribution of DXS6804, DXS7130, DXS7132 and DXS8378. The results showed that： the forensic application of five indicators compared with other ethnic groups and races are significantly different. The difference was statistically significant （P 〈0.05）. The results confirms DXS6804, DXS7130, DXS7132 and DXS8378 have feature of high genetic polymorphism, and is valuable in forensic individual identification and paternity testing, and enrich minority STR genetic databases.

关 键 词：短串联重复序列 X染色体 遗传多态性 土家族 法医学 

分 类 号：D919.1[医药卫生—法医学] Q347[政治法律—法学]