左旋咪唑在猪瘟疫苗接种猪中免疫调节作用的研究  

STUDY ON THE FUNCTION OF IMMUNE REGULATION OF LEVAMISOLE TO PIG INOCULATED BY SWINE FEWER VACCINE

作　　者：王世礼[1] 吴兴华 武占银 王进香 许立华 王晓亮 

机构地区：[1]宁夏农学院,宁夏永宁750105 [2]宁夏回族自治区兽医工作站,宁夏银川750002

出　　处：《宁夏农学院学报》2000年第3期11-13,共3页Journal of Ningxia Agricultural College

基　　金：宁夏教委资助项目

摘　　要：本研究采用 2 0头 40— 45日龄仔猪 ,随机分为试验组和对照组。两组猪只均肌肉接种猪瘟疫苗 1头份。从疫苗接种的当日开始 ,在试验组猪只饲料内按每天每公斤体重 8mg计算 ,拌入盐酸左旋咪唑 ,连服三日 ;对照组不服左旋咪唑。于接苗后的 10、40、70和 10 0天 ,分别由两组猪只耳静脉采血 ,分离血清 ,供测定血清抗体用。同时 ,分别取两组猪只血样作成血涂片 ,供检测T淋巴细胞用。试验结果 :除接苗后 40天 ,试验组与对照组血清抗体效价的几何平均数相同外 ,于接苗后的 10和10 0天 ,试验组血清抗体效价稍高于对照组 ,但两组间的差异不显著 (p >0 .0 5 )。于接苗后 10天 ,试验组T淋巴细胞的百分率显著高于对照组 (P <0 .0 5 )。由此可见 ,猪只在接种猪瘟疫苗的同时 ,服用左旋咪唑 ,可以促进T淋巴细胞的增殖 ,增强其免疫力。In the research, 20 heds of piglets at 40-45 days age were divided into two groups, that is experimental group and contrast group, randomly. All pigs were inoculated by swine fewer vaccine in routine dosage. The pigs in experimental group were fed by the feed mixed Levamisole hydrochloride 8mg/kg/day start from the first day after inoculation for 3 days. After inoculation 10, 40, 70 and 100 days the pigs both groups were collected blood, isolated serum, tested serum antibody respectively. In the same time, the blood of pigs both groups was made blood smear, to test T lymphocyte. The experimental results were: after inoculating 40 days, the geometry average of the serum antibody titer in pigs of both groups was same, after inoculating 10 and 100 days, the serum antibody titer of test group was more than of contrast group, the difference of both groups was no significant (P>0.05). After inoculating 10 days, the percentage of T Lymphocyte of test group was more than of contrast group. Therefore, the pigs were fed Levamisole as well as inoculated by swine fewer vaccine, it can promote rise of T Lymphocyte, increase immunity.

关 键 词：左旋咪唑 猪瘟疫苗接种猪 免疫调节作用 

分 类 号：S858.285.3[农业科学—临床兽医学] S859.799.9[农业科学—兽医学]