药对研究(Ⅷ)——丹参-红花药对  

Research of Chinese medicine pairs(Ⅷ)——Salviae Miltiorrhizae Radix et Rhizoma-Carthami Flos

作　　者：李淑娇[1] 唐于平[1] 沈娟[1] 李建萍[1] 郭建明[1] 段金廒[1] 

机构地区：[1]南京中医药大学江苏省方剂研究重点实验室,江苏省中药资源产业化过程协同创新中心,江苏南京210023

出　　处：《中国中药杂志》2013年第24期4227-4231,共5页China Journal of Chinese Materia Medica

基　　金：国家科技支撑计划项目(2008BAI51B01)

摘　　要：丹参-红花是著名的活血药对,丹参活血化瘀,红花活血通络,二者均为活血要药。丹红注射液是把丹参与红花按科学配方提取精制而成,是二者配伍的典型应用,主要用于治疗脏器供血不足和缺血梗塞性疾病,能够明显缓解心绞痛症状,改善心肌缺血,消退动脉粥样硬化斑块,抗血栓等。该文从功效物质、配伍效应与相关机制、临床应用方面对丹参-红花药对的近期研究进展进行了系统的阐述,以期进一步提升该药对的基础研究与应用水平。Salviae Mihiorrhizae Radix et Rhizoma-Carthami Flos is a famous Chinese medicine pair （CMP）. Salviae Miltiorrhizae Radix et Rhizoma can promote blood circulation for removing blood stasis, and Carthami Flos can promote blood circulation for removing meridian obstruction and remove blood stasis for relieving pain. The two herbs are important TCMs for activating blood. Dan- hong injection is the classic application of the two herbs compatibility, which was made from Salviae Mihiorrhizae Radix et Rhizoma and Carthami Flos with scientific formalation by extraction and refining. The CMP is used for treatement of organ flood insufficiency and ischemic infarction diseases. It can obviously relieving symptoms of angina pectoris, improve myocardial ischemia, regress atherosclerosis plaque, and inhibit thrombus. This paper elaberated the bio-active constituents, compatibility effects and action mechanism, and clinical applications of the CMP in order to further upgrade basic research and application levels of the CMP.

关 键 词：丹参 红花 药对 丹红注射液 功效物质 配伍效应 临床应用 

分 类 号：R285[医药卫生—中药学]