复方丹参脉冲胶囊处方筛选和制备工艺研究  

Study on prescription screening and preparation process of compound Danshen pulse capsule

作　　者：李鑫[1] 王晓扬[1] 武文强[1] 赵金凤[1] 李津明[2] 

机构地区：[1]哈尔滨商业大学药学院,黑龙江哈尔滨150076 [2]厦门医学高等专科学校,福建厦门361008

出　　处：《中国中药杂志》2013年第24期4309-4313,共5页China Journal of Chinese Materia Medica

摘　　要：该试验以复方丹参为模型药物,研制胃浮型溶蚀塞型脉冲胶囊,实现中药的脉冲释放。通过对非渗透性胶囊体的研制及处方优选考察,含药速释片的研制及处方筛选,溶蚀塞的处方及工艺考察以及助漂浮剂选择成功制备了复方丹参脉冲胶囊,为控制心脏病的治疗提供新剂型,使其更好的适应临床需要。To develop gastric floating erodible plug pulse capsules with compound Danshen as the model drug, in order to realize the pulse release of traditional Chinese medicines. Through the study on impermeable capsules, optimized prescriptions, drug-containing rapid-release tablets and prescription screening, and erodible plug prescription and process, we successfully prepared compounded Danshen pulse capsule, so as to provide a new dosage form for controlling and treating heart disease to better eater to clinical demands.

关 键 词：复方丹参 脉冲胶囊 溶蚀塞 胃漂浮 

分 类 号：R286[医药卫生—中药学]