复杂形貌磁性复合微球制备及其生物应用  

Synthesis and Biomedical Applications of Magnetic Nanocomposites with Complex Morphologies

作　　者：李恬[1,2] 王祎龙[2] 郭方方[2] 时东陆[2] 

机构地区：[1]同济大学材料科学与工程学院,上海200092 [2]同济大学医学院生物医学工程与纳米科学研究院,上海200092

出　　处：《化学进展》2013年第12期2053-2067,共15页Progress in Chemistry

基　　金：国家自然科学基金项目(No.51173135);上海市科委纳米专项(No.11nm0506100);中央高校基本科研业务费专项资金资助

摘　　要：具有复杂形貌的磁性复合材料显示出独特的物理和化学性质,在药物载体、体外生物检测、体内成像和磁转染、磁热疗等生物医学领域具有良好的应用前景。本文就几种典型的除简单核-壳结构外的磁性复合材料的形貌和结构分类、制备方法和应用研究进展进行了全面的综述,主要包括Janus、Yolk-Shell和介孔结构复合微球的相关研究,并对复杂形貌的磁性复合微球制备技术的改进及应用上的拓展作出展望。Magnetic nanocomposites with complex structures physical and chemical properties. Their applications in the drug and surface functionalities show the unique carrier, bio-detection, in vivo imaging and catalysts are very promising. In this review, several typical magnetic composites with complex architectures, including Janus structure, Yolk-Shell shape and mesoporous structure composite are thoroughly discussed, the progresses in preparation method and biomedical applications are reviewed. The outlook of improvement of fabrication technology and potential applications are also concerned.

关 键 词：复杂形貌 非对称结构 磁性复合微球 生物应用 

分 类 号：O614.81[理学—无机化学] TB33[理学—化学]