四水合三氟磺酸铋催化合成柠檬酸三丁酯  

CATALYTIC SYNTHESIS OF TRIBUTYL CITRATE WITH BISMUTH TRIFLATE TETRAHYDRATE

作　　者：何林[1] 高敬芝[2] 李文娟[1] 王卫[1] 代斌[1] 

机构地区：[1]石河子大学化学化工学院/新疆兵团化工绿色过程重点实验室,新疆石河子832000 [2]石河子大学师范学院,新疆石河子832000

出　　处：《精细石油化工》2013年第6期39-42,共4页Speciality Petrochemicals

基　　金：兵团博士资金资助项目(2011BB011)

摘　　要：研究了路易斯酸Bi(OTf)3·4H2O催化下,一水合柠檬酸与正丁醇通过分子间酯化合成绿色增塑剂柠檬酸三丁酯的反应。通过单因素实验,考察了催化剂用量、反应时间、酸醇物质的量比和反应温度等因素对反应的影响。进一步通过正交试验,综合考察了各因素对酯化率的影响,确定了最佳反应条件:催化剂用量2%,酸醇摩尔比1∶4,反应温度140℃,反应时间为3.5h,酯化率可达到98%以上。另外,催化剂可以循环利用多次,酯化率仍保持在较高水平。The esterification reaction of citric acid and n-butyl alcohol to synthesize tributyl citrate catalyzed by Bismuth triflate tetetrahydrate was investigated. The effects of catalyst loading, the ratio of citric acid and n-butyl alcohol, reaction time and temperature were studied via single-factor experiments, and the optimal reaction parameter was determined by the orthogonal test. With 2% Bi（OTf）3 . 4H2O and a four-fold excess of n-butyl alcohol, the final yield of tributyl citrate can be obtained above 98% after reacting at 140 ℃ for 3.5 h. In addition, the catalyst can be separated from the reaction mixture very easily, which can be used for many times without obvious decreasing of the reaction yield.

关 键 词：三氟磺酸铋 柠檬酸三丁酯 柠檬酸 正丁醇 催化合成 

分 类 号：TQ414.99[化学工程]