布洛芬印迹聚合物的制备及水相中的识别特性  

Preparation of Ibuprofen Imprinted Polymer and Its Recognition Characteristics in Aqueous Solvents

作　　者：皇甫风云[1,2] 王兵[2] 单娟娟[1] 孔媛媛[1] 

机构地区：[1]天津工大纺织助剂有限公司天津工业大学,天津300160 [2]天津工业大学中空纤维膜材料与膜过程省部共建国家重点实验室培育基地环境与化学工程学院,天津300160

出　　处：《高分子材料科学与工程》2013年第12期35-38,42,共5页Polymer Materials Science & Engineering

基　　金：天津市自然科学基金重点项目(13JCQNJC02600)

摘　　要：以布洛芬为模板、4-乙烯基吡啶为功能单体,在强极性溶剂N,N-二甲基甲酰胺中制备了可以在水相中实现特异性识别的布洛芬印迹聚合物。利用紫外光谱、红外光谱研究了模板分子与功能单体的作用情况。静态氮吸附法(BET)表明印迹聚合物的比表面积明显大于非印迹聚合物。系统考察了水相中印迹聚合物的识别特性,结果表明,布洛芬印迹聚合物对布洛芬表现出明显的吸附选择性,对其结构类似物酮洛芬、萘普生的吸附选择性较差,分离因子分别为3.29和3.95。利用透射电镜对印迹聚合物的再生性能进行了考察,结果表明制备的印迹聚合物具有良好的洗脱再生性能。Ibuprofen imprinted polymer was prepared in strong polar solvent （N, N-dimethylformamide） using ibuprofen as template and 4-vinytpridine as functional monomer, which could achieve a specific recognition in aqueous solvents. The interaction between functional monomer and ibuprofen was verified by UV-visible spectroscopy and infrared spectra. Molecularly imprinted polymer （MIP） was analyzed by Brunauer, Emmet and Teller adsorption （BET）. The results show that the surface area of MIPs is larger than that of non-imprinted polymers. The binding performance of MIP in aqueous solvents was studied systematically. The results indicate that compared with structural analogs of ibuprofen （such as naproxen and ketoprofen）, MIP exhibits a significant adsorption selectivity for ibuprofen. The separation factors are 3.29 and 3.95, respectively. The repeatability of MIP was studied by transmission electron microscopy, showing that MIP prepared has an excellent elution property and can be easily regenerated and reused.

关 键 词：布洛芬 印迹聚合物 水相 识别特性 

分 类 号：TB34[一般工业技术—材料科学与工程]