微流控芯片中酶的固定化及表面修饰应用  

Enzyme Immobilization and Surface Modification Application on Microfluidic Device

作　　者：唐修雯 张琴[1] 陈缵光[1] 成志毅[1] 

机构地区：[1]中山大学药学院,广东广州510006

出　　处：《分析科学学报》2013年第6期865-869,共5页Journal of Analytical Science

摘　　要：近年来,微流控芯片分析发展迅速,以其样品量少、分析时间短、仪器体积小、功能集成化和自动化等优势吸引了各分析领域研究者们的关注。本文总结归纳了微流控芯片反应体系中酶的固定方法、芯片材料与表面修饰以及微流控芯片技术的相关应用,重点介绍微流控芯片上酶的化学固定法、物理固定法以及免疫固定法。Microfluidic device has attracted for the advantages of less reagent consumption, reduced reaction time, miniaturized architecture and automation. In this review, we summarize the method of enzyme immobilization, materials for microfluidic chip and surface modification, application of microfluidic device, and emphasis on immobilization of enzyme on microfluidic chip using chemical, physical and immunological methods.

关 键 词：微流控芯片 固定化 酶 

分 类 号：O657[理学—分析化学]