门诊患者^13C呼气试验检测幽门螺杆菌的调查分析  

^(13)C-urea breath test for detection of Helicobacter pylori in outpatient department

作　　者：邸岩[1] 高炳霞[1] 齐颖[1] 宋丹萍[1] 苗丽[1] 李志刚[2] 

机构地区：[1]首都医科大学附属北京世纪坛医院老年科,北京100038 [2]北京中医药大学针灸推拿学院消化专业,北京100029

出　　处：《中华医院感染学杂志》2013年第24期5960-5962,共3页Chinese Journal of Nosocomiology

基　　金：高等学校博士学科点专项科研基金资助项目(200800260002)

摘　　要：目的研究门诊13 C-尿素呼气试验检查患者的临床特征及相关因素,探索临床症状对13 C-尿素呼气试验检查的指导作用。方法以问卷调查形式,收集2013年3月1日-6月1日门诊行13 C-呼气试验检查150例患者的资料进行分析,应用SPSS14.0软件进行数据分析,应用logistic回归筛选检出相关的因素。结果共获得有效问卷128份,幽门螺杆菌感染阳性者58例占45.3%;临床症状:报警20例占15.6%,消化不良22例占17.2%,反流18例占14.1%,重叠30例占23.4%,其他症状38例占29.7%;多因素logistic回归分析结果显示,上腹部烧灼感、胸骨后疼痛和便秘与幽门螺杆菌感染密切相关(P<0.05);饮酒是幽门螺杆菌感染阳性的相关因素(P<0.05)。结论基于幽门螺杆菌感染在功能性消化不良、反流性食管炎、便秘等疾病发病机制中的作用,上腹部烧灼感、胸骨后疼痛、便秘症状对于筛选13 C-尿素呼气试验检查、提高消化科门诊成本效益具有一定的意义。OBJECTIVE To study the clinical characteristics and related factors for the outpatient department patients undergoing the 13C-urea breath test so as to explore the role of clinical symptoms in guiding the 13C-urea breath test. METHODS By means of questionnaire survey, the data of 150 patients who underwent the 13C-urea breath test in the outpatient department from Mar 1 to Jun 1, 013 were collected and analyzed, then the statistical analysis of the data was performed with the use of SPSS14.0 software, and the logistic regression analysis was conducted to screen out the related factors. RESULTS Totally 128 valid questionnaires have been recovered. The Helicobacter pylori infection occurred in 58 （45.3%） cases. Among the cases of clinical symptoms, there were 20 （15.6%） cases of alarming, 22 （17.2%） cases of dyspepsia, 18 （14.1%） cases of reflux, 30 （23.4%） cases of overlapping, and 38 （29.7%） cases of other symptoms. The result of multivariate logistic regression analysis indicated that the H. pylori infection was related to the epigastic burning, etrosternal pain, and constipation（P〈0.05）; alcohol intake was the related factor for the H. pylori infection （P%0.05）. CONCLUSION As based on the role of H. pylori infection in the pathogenesis of functional dyspepsia, reflux esophagitis, and constipation, the epigastic burning, retrosternal pain, and constipation have certain significance in screening out the ^13C-urea breath test and increasing the cost effectiveness of gastroenterology department.

关 键 词：^13C尿素呼气试验 幽门螺杆菌 症状 胃食管反流病问卷 

分 类 号：R181.32[医药卫生—流行病学]