中国健康人血清胆固醇酯转运蛋白水平  

Serum Cholesteryl Ester Transfer Protein Levels in Healthy Chinese Subjects

作　　者：庄一义[1] 汪俊军[1] 刘小传[1] 李勇[1] 强红娟[1] 李露言[2] 陈光辉[3] 

机构地区：[1]南京军区南京总医院全军医学检验中心生化室,南京210002 [2]南京军区南京总医院心内科,南京210002 [3]南京军区南京总医院神经内科,南京210002

出　　处：《中国动脉硬化杂志》2000年第4期289-291,共3页Chinese Journal of Arteriosclerosis

基　　金：军队九五科研基金课题(1996D025)

摘　　要：为研究中国健康人血清胆固醇酯转运蛋白水平和分布特征 ,采用“Sandwich”酶免疫法测定了 112 8例健康人群血清胆固醇酯转运蛋白水平 ,结果为 1.84± 1.5 5mg/L ,胆固醇酯转运蛋白水平倾向于低浓度的偏态分布 ,女性胆固醇酯转运蛋白水平明显高于男性 (分别为 2 .40± 1.6 5mg/L和 1.49± 1.37mg/L ,P <0 .0 0 1)。胆固醇酯转运蛋白水平与年龄之间呈显著的负相关 (r=- 0 .19,P <0 .0 0 1) ,与其他各项血脂浓度间均无相关性。Aim To determine the serum CETP concentration in 1 128 healthy Chinese subjects, and to analyze the characteristics of CETP level and distribution in different age and sex groups. Methods The CETP concentration was determined using “Sandwich” ELISA. Results The CETP level was 1.84±1.55 mg/L. The frequency distribution of CETP in healthy subjects was markedly skewed to low concentration. The frequency distribution of CETP in female was significantly higher than that in male (2.40±1.65 mg/L vs. 1.49±1.37 mg/L,P<0.001). There was a highly inverse correlation between the CETP level and age (r=-0.19,P<0.001), while no relation was found between CETP level and lipids concentration. Conclusion The regular pattern of serum CETP in 1 128 healthy Chinese subjects has been demonstrated.

关 键 词：胆固醇酯 转运蛋白 人群 参考值 血脂 动脉粥样硬化 

分 类 号：R543.5[医药卫生—心血管疾病]