老年原发性高血压患者血压变异性及其与颈动脉病变的相关性研究  被引量:9

Relationship between blood pressure variability and carotid artery disease in elderly patients with primary hypertension

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作  者:董艳娟[1] 张春驰[1] 周冬翠[2] 

机构地区:[1]北京军区总医院东楼干部病房三科,100700 [2]北京军区总医院东楼干部病房一科,100700

出  处:《中国医师进修杂志》2013年第34期1-3,共3页Chinese Journal of Postgraduates of Medicine

摘  要:目的 通过对老年原发性高血压患者血压变异性(BPV)及其与颈动脉内膜-中层厚度(IMT)的观察研究,分析老年原发性高血压患者BPV的特点及其与动脉粥样硬化的关系.方法 109例老年原发性高血压患者,均进行24 h动态血压监测(ABPM),记录24h平均收缩压(24h SBP)、24h平均舒张压(24h DBP)及其标准差;日间平均收缩压(dSBP)、日间平均舒张压(dDBP)及其标准差;夜间平均收缩压(nSBP)、夜间平均舒张压(nDBP)及其标准差.并计算各自的变异系数(CV).所有患者均进行颈动脉超声检查,测量颈动脉IMT.109例患者按颈动脉IMT结果分为非颈动脉硬化组(IMT< 1.0 mm,49例)和颈动脉硬化组(IMT≥1.0 mm,60例).结果 颈动脉硬化组dSBP以及24 h平均收缩压变异系数、24h平均舒张压变异系数、日间平均收缩压变异系数、夜间平均收缩压变异系数均明显高于非颈动脉硬化组[(132.3±12.1) mm Hg(1 mm Hg=0.133 kPa)比(122.7±10.8) mm Hg、0.118±0.011比0.107±0.023、0.142±0.058比0.116±0.028、0.129±0.039比0.105±0.017、0.119±0.060比0.109±0.037],差异有统计学意义(P< 0.01或<0.05).两组24 hSBP、24 h DBP、dDBP、nSBP、nDBP、日间平均舒张压变异系数、夜间平均舒张压变异系数比较差异无统计学意义(P>0.05).结论 颈动脉硬化的老年原发性高血压患者BPV明显高于非颈动脉硬化的老年原发性高血压患者,BPV与颈动脉IMT有一定的相关性.Objective To observe blood pressure variability (BPV) in elderly patients with primary hypertension and carotid artery intima-media thickness (IMT),and analyze the correlation between BPV and atherosclerosis.Methods One hundred and nine patients with primary hypertension were divided into non-carotid atherosclerosis group (IMT 〈 1.0 mm,49 cases) and carotid atherosclerosis group (IMT ≥ 1.0mm,60 cases).24 h ambulatory blood pressure monitoring (ABPM) was used to measure the 24-hour mean systolic blood pressure (24 h SBP),24-hour mean diastolic pressure (24 h DBP) ; SBP of daytime (dSBP)and nighttime (nSBP) ; DBP of daytime (dDBP) and nighttime (nDBP).And their standard deviation and coetficient of variation (CV) was calculated.Results dSBP,24 h SBPCV,24 h DBPCV,dSBPCV,nSBPCV in carotid atherosclerosis group was higher than that in non-carotid atherosclerosis group [(132.3 ± 12.1)mm Hg(1 mm Hg =0.133 kPa) vs.(122.7 ± 10.8) mm Hg,0.118±0.011 vs.0.107 ± 0.023,0.142 ± 0.058vs.0.116 ±0.028,0.129 ±0.039 vs.0.105 ±0.017,0.119 ±0.060 vs.0.109 ±0.037],and there was significant difference (P 〈 0.01 or 〈 0.05).There was no significant difference in 24 h SBP,24 h DBP,dDBP,nSBP,nDBP,dSBPCV,nSBPCV between two groups (P 〉0.05).Conclusions BPV of carotid atherosclerosis is higher than that of non-carotid atherosclerosis.BPV and carotid artery IMT has a certain relevance.

关 键 词:高血压 颈动脉疾病 

分 类 号:R544.1[医药卫生—心血管疾病]

 

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