Synthesis,Characterization,and Linear and Nonlinear Optical Properties of Phenylene-vinylene Based Chromophores for Singlet Oxygen Generation  

作　　者：王淑容 汤昌泉 郑庆东 

机构地区：[1]State Key Laboratory of Structural Chemistry,Fujian Institute of Research on the Structure of Matter,Chinese Academy of Sciences [2]Graduate University of Chinese Academy of Sciences

出　　处：《Chinese Journal of Structural Chemistry》2013年第11期1687-1695,共9页结构化学（英文）

基　　金：National Natural Science Foundation of China(21102144);in part supported by 100 Talents Programme of Chinese Academy of Sciences

摘　　要：A series of symmetrical and unsymmetrical phenylene-vinylene （PV） based chro- mophores with the molecular configuration of donor-π-donor （D-g-D） were prepared and characterized. Iodine was first introduced into the Jr-conjugation backbone of the PV based chromophores in order to study the heavy atom effect on their linear absorption, two-photon absorption （TPA） properties, as well as singlet oxygen generation properties. TPA cross-sections of these chromophores were investigated by using the two-photon excited fluorescence method. The unsymmetrical chromophores were found to have larger TPA cross-section values compared to their symmetrical counterparts. For one of the unsymmetrical chromophores with the iodine incorporation, a large TPA cross section value with quenched emission was found. The decreased fluorescence quantum yield of a molecule can be ascribed to the increased intersystem crossing, which is favorable for enhancing the singlet oxygen generation. Therefore, the unsymmetrical PV based chromophores with heavy atom incorporation are promising singlet oxygen sensitizers for the photodynamic therapy application.A series of symmetrical and unsymmetrical phenylene-vinylene （PV） based chro- mophores with the molecular configuration of donor-π-donor （D-g-D） were prepared and characterized. Iodine was first introduced into the Jr-conjugation backbone of the PV based chromophores in order to study the heavy atom effect on their linear absorption, two-photon absorption （TPA） properties, as well as singlet oxygen generation properties. TPA cross-sections of these chromophores were investigated by using the two-photon excited fluorescence method. The unsymmetrical chromophores were found to have larger TPA cross-section values compared to their symmetrical counterparts. For one of the unsymmetrical chromophores with the iodine incorporation, a large TPA cross section value with quenched emission was found. The decreased fluorescence quantum yield of a molecule can be ascribed to the increased intersystem crossing, which is favorable for enhancing the singlet oxygen generation. Therefore, the unsymmetrical PV based chromophores with heavy atom incorporation are promising singlet oxygen sensitizers for the photodynamic therapy application.

关 键 词：two-photon absorption phenylene-vinylene based chromophore singlet oxygen generation heavy atom effect 

分 类 号：O621.3[理学—有机化学]