蠲痹灸联合甲氨蝶呤治疗难治性类风湿关节炎临床观察  

Clinical Observation on Juanbi Moxibustion Combined with Methotrexate treatment of Refractory Rheumatoid Arthritis

作　　者：叶仿武[1] 朱峪英[1] 吴理扬[1] 沈维[1] 

机构地区：[1]中国人民解放军第三0三医院,广西南宁530021

出　　处：《实用中西医结合临床》2013年第8期12-13,共2页Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine

摘　　要：目的:观察蠲痹灸联合甲氨蝶呤治疗难治性类风湿性关节炎的疗效及副作用。方法:80例难治性类风湿性关节炎患者随机分两组。对照组给予甲氨蝶呤口服,观察组在对照组基础上联合蠲痹灸治疗,观察时间为3个月。结果:对照组的总有效率为60.0%,观察组为95.0%,两组的疗效差异有统计学意义(P<0.05),以观察组的疗效为优;观察组治疗后ESR、RF、CRP与对照组比较,差异有统计学意义(P<0.05);两组肝肾功能均未见明显异常,未发生副作用。结论:蠲痹灸与甲氨蝶呤联合应用治疗难治性类风湿性关节炎效果明显,并且联合应用副作用未见增加。Objective： To observe the efficacy and side effects of Juanbi moxibustion combined with methotrexate treatment of refractory rheumatoid arthritis.Methods： 80 Patients with refractory rheumatoid arthritis were randomly divided into two groups. Control group and observation group： methotrexate was given orally; observation group： add Juanbi moxibustion treatment, observation period of 3 months. Results： In the control group, the total effective rate was 60.0%, In the observation group was 95.0%, the efficacy of the two groups was statistically significant difference （P〈0.05）; ESR, RF, CRP of observation group aRer treatment, compared with the control group, The difference was statistically significant （P〈0.05）; no obvious abnormalities in liver and kidney function, no side effects was found in two group. Conclusion： The efficacy of Juanbi moxibusfion combined with methotrexate treatment of refractory rheumatoid arthritis is obvious, and no increase in side effects of the combination.

关 键 词：难治性类风湿关节炎 蠲痹灸 甲氨蝶呤 中西医结合疗法 

分 类 号：R593.22[医药卫生—内科学]