血流动力学的医学应用与发展  

Recent development and application of hemodynamics

作　　者：白帆[1] 刘有军[1] 谢进生[2] 丁金立[1] 王枫[1] 赵夕[1] 任晓辰[1] 乔爱科[1] 

机构地区：[1]北京工业大学生命科学与生物工程学院,北京100124 [2]北京安贞医院心脏外科,北京100029

出　　处：《医用生物力学》2013年第6期677-683,共7页Journal of Medical Biomechanics

基　　金：国家自然科学基金资助项目(11172016);北京市自然科学基金重点资助项目(KZ201210005006)

摘　　要：血流动力学是指血液在血管系统中流动的力学,主要研究血流量、血流阻力、血压、切应力、扰动流等,以及它们之间的相互关系,对人类生命健康具有重要的影响。血流动力学在血管的弯曲、狭窄、堵塞、分叉以及肿瘤的治疗等方面具有重要的临床研究意义。目前,血流动力学在动脉血管搭桥、冠状动脉狭窄、腹主动脉瘤、动脉粥样硬化、脑动脉肿瘤以及旋动流等方面引起广泛研究。伴随着血流动力学的深入研究,心脑血管的手术规划、介入治疗等得到快速发展,基于血流动力学的临床检测和治疗仪器也越来越多。血流动力学因素,如血管压力、血管阻力、血流量、壁面切应力、血液黏度、流动分离、湍流、涡流等对常见血管疾病以及术后并发症的影响机理正在逐步深入探索之中,并已经取得了一定成果。The study of hemodynamics, which refers to dynamics inside the blood circulation, mainly includes the flow rate, flow resistance, pressure, shear stress, disturbed flow, as well as their associations in between. Therefore, with its important significance in the clinical treatments of vessel curvature, arterial stenosis or occlusion, pathological artery branches and aneurism, study about hemodynamics is essential to human health. Currently, extensive researches on hemodynamics have been conducted with respect to artery bypass, coronary arterial stenosis, abdominal aortic aneurysm, atherosclerosis, cerebral aneurysm and swirling flow. With the development of such research on hemodynamics, surgical planning and interventional therapy have improved rapidly. The influence mechanism of hemodynamic parameters, including pressure, flow resistance, flow rate, wall shear stress, blood viscosity, flow separation, turbulent flow, vortex on the post-operation complications could be deeply explored with the help of more and more clinical apparatus and have gained some achievements.

关 键 词：血流动力学 动脉疾病 手术规划 介入治疗 医疗仪器 

分 类 号：R318.01[医药卫生—生物医学工程]