适宜中药特性的粉体改性技术方法研究  

Study on powder modification technology for Chinese materia medica characteristics

作　　者：韩丽[1] 张定堃[1] 林俊芝 张芳[1] 杨明[1,3] 邹文铨[4] 

机构地区：[1]成都中医药大学中药资源系统研究与开发利用省部共建国家重点实验室培育基地,四川成都611137 [2]成都中医药大学附属医院,四川成都610072 [3]江西中医药大学现代中药制剂教育部重点实验室,江西南昌330004 [4]四川大学化学学院,四川成都610064

出　　处：《中草药》2013年第23期3253-3259,共7页Chinese Traditional and Herbal Drugs

基　　金：国家自然科学基金资助项目(30973952;81274098);四川省重大产业技术创新专项(2011ZY00299)

摘　　要：粉体是中药固体制剂制备的基础,粉体的性质深刻影响着后续的制剂工艺与质量评价。中药粉体由于其理化性质复杂而特殊,如何有效地改变粉体的性质,是中药药剂学需要解决的关键科学问题之一。近10年来,药剂学工作者对适宜中药特性的粉体改性技术进行了卓有成效的研究,结合近年来的研究成果对中药粉体改性技术的研究方法进行总结,以期抛砖引玉,推动中药粉体改性技术的进步与发展。Powder is the basis of solid preparation in Chinese materia medica （CMM）, its properties have a great effect on the following preparation technology and its quality evaluation. Exploring the method for the powder modification technology is the key issues in pharmaceutics, due to the complicated and unusual physicochemical properties of CMM powder. Nearly ten years, tough and fruitful work has been carried out in this field. On the basis of other experts＇ achievements and their work experience, this paper reviews the modification technology for CMM powder initially, so as to promote the development of powder modification technology for CMM.

关 键 词：中药粉体 粉体改性技术 改性原理 改性方法 质量评价 

分 类 号：R283[医药卫生—中药学]