福建省2005-2012年人群流感抗体水平监测  

Surveillance on influenza antibody levels in Fujian population (2005-2012)

作　　者：杨式芹[1] 洪荣涛[1] 陈秋虾 何芸 谢剑锋[1] 翁育伟[1] 

机构地区：[1]福建省疾病预防控制中心,福州350001 [2]漳州市疾病预防控制中心,福建363000 [3]龙岩疾病预防控制中心,福建364000

出　　处：《海峡预防医学杂志》2013年第4期15-17,共3页Strait Journal of Preventive Medicine

摘　　要：目的了解福建省监测点人群流感抗体水平,初步预测流行趋势。方法福建省监测点人群每年按5个年龄组各采集20份血清,用血凝抑制试验法检测抗体效价,分析分布特征。结果 2005-2012年全省新H1N1、H1N1、H3N2、BY和BV型抗体阳性率分别为34.5%、39.8%、56.4%、36.0%、17.2%;保护率分别为18.0%、14.8%、31.5%、25.7%和8.6%;5种型别抗体GMT总的态势是H3N2最高、BV最低。结论福建省监测点人群流感抗体水平整体较低,BV有流行、暴发可能,新H1N1流行风险大于H1N1,目前推荐的含有新H1N1成分的流感疫苗适合人群免疫接种。Objective To investigate the levels of influenza antibodies of population of surveillance sites in Fujian and predict the influenza epidemic trends.Methods Totally 20samples of blood serum were collected from five age groups（2005-2012）.The antibody levels were detected by using blood agglutination inhibition test and the epidemiological characteristics were analyzed.Results From 2005to 2012,the positive rates of new H1N1,H1N1,H3N2,BY,and BV were 34.5%,39.8%,56.4%,36.0%,and 17.2%,respectively.The protection rates were 18.0%,14.8%,31.5%,25.7% and 8.6%,respectively.In the five types,the overall antibody GMT trend shown that the highest titer was H3N2,the lowest one was BV.Conclusion The overall antibody level in Fujian population is at lower level.Type BV may be in the risk of epidemic or outbreak.The epidemic risk of new H1N1is greater than that of H1N1.The current recommended flu vaccine containing the ingredient of new H1N1is suitable for the population immunization.

关 键 词：流感 血凝抑制试验 流感抗体 福建省 

分 类 号：R373.1[医药卫生—病原生物学]