福建省AIDS病人治疗1年后CD4^+T淋巴细胞变化及影响因素分析  

Analysis on the change of CD4^+T cell and the influencing factors in AIDS patients after one year treatment in Fujina,China

作　　者：邱月锋[1] 颜苹苹[1] 吴守丽[1] 梁菲菲[1] 谢美榕[1] 夏品苍[1] 

机构地区：[1]福建省疾病预防控制中心,福州350001

出　　处：《海峡预防医学杂志》2013年第5期4-6,共3页Strait Journal of Preventive Medicine

基　　金：福建省自然科学基金(No.2009J01104)

摘　　要：目的分析福建省AIDS病人抗病毒治疗后CD4+T淋巴细胞变化情况,探讨影响因素。方法将治疗满1年的AIDS病人CD4+T淋巴细胞计数与基线时进行比较,用logistic回归分析影响因素。结果接受治疗1年以上患者CD4+T淋巴细胞计数升高明显。年龄≥30岁、静脉吸毒、曾经停药、基线反复的细菌性肺炎是主要危险因素。结论在我省抗病毒治疗1年以上的患者,其CD4+T淋巴细胞免疫重建良好。ObjectiveTo investigate the change of CD4^＋T cell in AIDS patients after treatment for one year and explore the influencing factors.Methods The counts of CD4^＋T cell between baseline and the level after one year treatment were compared and the influencing factors were analyzed by logistic regression model.Results After one year treatment,the CD4^＋T cells increased significantly.The main risk factors for CD4^＋T cell change were as follows：age≥ 30,taking drugs with intravenous injection,suspended treatment and bacterial pneumonia.Conclusion The recovery of immune system of AIDS patients after anti-virus treatment for one year is satisfactory.

关 键 词：艾滋病(AIDS) CD4+T淋巴细胞 抗病毒治疗 治疗效果 

分 类 号：R512.91[医药卫生—内科学]