免疫细胞化学在胸腹水细胞学诊断中的应用  

Immunocytochemical Studies on Cytological Diagnosis of Ascites and Hydrothorax

作　　者：王雅如[1] 朱云华[1] 朱长乐[1] 柳志向[1,2] 包国祥[1,2] 于振键 

机构地区：[1]江苏省中医院病理科,210029 [2]江苏职工医科大学,210029 [3]南京市第一卫生学校,210000

出　　处：《镇江医学院学报》1999年第4期540-542,共3页Journal of Zhenjiang Medical College

摘　　要：目的:探讨免疫细胞化学在细胞学诊断中的应用。方法:用常规技术和免疫细胞化学方法对70例胸腹水标本进行观察。结果:47例检出恶性和异型增生细胞,23例检测出良性和增生间皮细胞,CEA阳性率分别为55.3%,17.3%,差异显著。根据CEA、EMA、Keratin、Vimentin的表达有6例识别转移癌和增生间皮细胞。根据AFP、MG-7表达帮助确定6例肿瘤的原发灶。结论:免疫细胞化学能提高胸腹水细胞学诊断的准确性。objective: To explore the application of immnocytochemical methods in cytological diagnosis.Methods: Seventy cases of ascites and hydrothorax were investigated using routine techniques and immunocytochemical methods.Results: 47 cases were detected malignant and dysplasia cells.23 cases were detected benign and hyperplasia cells.The CEA positive rates were 55.3% and 17.3% respectively( P <0 05).According to the expressions of CEA,EMA,Keratin,Vimentin were diffrentiated between metastatic and hyperplasia mesothelial cells in 6 cases.According to the expressions of AFP,MG 7 were detected the locations of primary neoplasms in 6 cases.Conclusions: Immunocytochemistry may be increased the definete of cytological diagnosis.\;

关 键 词：细胞学诊断 免疫细胞化学 胸水 腹水 

分 类 号：R561.404[医药卫生—呼吸系统]