比较罗哌卡因复合与不复合舒芬太尼硬膜外规律间断注药用于分娩镇痛的临床效果  

Comparing the analgesic efficacy of ropivacaine with and without sufentanil epidural regular intermittent injection in parturients during labor

作　　者：丁秀花[1] 朱新杰[2] 杜冬萍[3] 何亮亮[4] 

机构地区：[1]上海交通大学附属第六人民医院奉贤分院妇产科,201400 [2]上海交通大学附属第六人民医院麻醉科,201400 [3]上海交通大学附属第六人民医院疼痛科,200233 [4]首都医科大学附属宣武医院疼痛科,100053

出　　处：《实用疼痛学杂志》2013年第4期255-258,共4页Pain Clinic Journal

摘　　要：目的评价硬膜外规律间断注药方式复合与不复合舒芬太尼用于分娩镇痛的临床效果。方法要求分娩镇痛的初产妇60例，随机分为舒芬太尼组（S组）和无舒芬太尼组（N组），各30例。S组为0．1％罗哌卡因与舒芬太尼0．4μg／ml；N组为0．1％罗哌卡因。结果与镇痛前相比，两组产妇镇痛后VAS均明显降低（P〈0．05），但两组间VAS比较差异无统计学意义（P〉0．05）。两组镇痛期间罗哌卡因用量与爆发痛发生率比较差异无统计学意义（P〉0．05），但S组瘙痒发生率明显高于N组（P〈O．05）。结论不复合舒芬太尼硬膜外规律间断（0．1％罗哌卡因，5ml／45min）注药方式用于分娩镇痛的镇痛效果确切且可明显降低产妇瘙痒发生率。Objective To evaluate the efficacy of ropivacaine epidural regular intermittent in- jection（ERII） in parturients during labor analgesia with or without sufentanil. Methods Sixty partu- rients who requested labor analgesia were randomly divided into two groups： group of sufentanil （group S）and group of non-sufentanil（group N）, thirty caseg in each group. The parturients in group S received 0.1% ropivacaine combined with 0.4 9g/ml sufentanil and group N only received 0.1% ropivacaine. Results VAS was obviously decreased in the two groups since receiving labor an- algesia （P〈0.05）, but no significant difference in VAS was found between the two groups （P〈 0.05）. During the labor analgesia, the incidence of breakthrough pain and consumption of ropiva- caine were similar between the two groups （P〉0. 05）. Compared with group S, the incidence of itching was lower in group N （P〈 0.05）. Conclusion Epidural regular intermittent injection of 0.1 % ropivacaine without sufentanil has a satisfactory analgesia and low incidence of itching during labor analgesia.

关 键 词：镇痛 硬膜外 规律 间断 产科 舒芬太尼 

分 类 号：R714.3[医药卫生—妇产科学]