经皮椎体成形术后椎体再发骨折的危险因素分析  

Analysis of the risk factors of new vertebral body fracture after percutaneous vertebroplasty

作　　者：易志坚[1] 曹家树[1] 王茂林[1] 温立升[1] 吴冲[1] 刘乐[1] 卢明刚[1] 

机构地区：[1]解放军第148医院骨科,山东淄博255300

出　　处：《颈腰痛杂志》2013年第6期474-476,共3页The Journal of Cervicodynia and Lumbodynia

摘　　要：目的探讨经皮椎体成形(Percutaneous Vertebroplasty,PVP)术后椎体再发骨折的发生机制及危险因素。方法回顾分析我院2006-03-2011-01月行经皮椎体成形术患者96例(137个椎体),动态监测其术后状态及正常椎体再发骨折情况,对患者年龄,性别,骨密度,初始骨折的节段,骨水泥注入量,骨水泥椎间隙渗漏,局部矢状面后凸成角,椎体高度恢复、抗骨质疏松治疗进行统计学分析。结果术后21例病人32个椎体新发骨折,其中18个椎体为邻近椎体,低骨密度、椎体高度过度恢复、骨水泥渗漏有统计学意义(P<0.05)。结论低骨密度、椎体高度过度恢复、骨水泥椎间隙渗漏是PVP术后新发椎体骨折的独立危险因素。术后坚持抗骨质疏松药物治疗能够降低新发椎体骨折的发生。Objective To investigate the patterns and risk factors of newly developed vertebral compression fractures after pereutaneous vertebroplasty（PVP）. Methods The clinical data of 96 pa- tients treated with PVP from March 2006 to January 2011 in our hospital were retrospectively ana- lyzed. The age,gender,bone mineral density （BMD）,level of initial fracture,volume of polymethyl- methacrylate,intradiseal cement leakage,local kyphotic angle,restoration rate of vertebral height,an- ti-osteoporosis treatment were statistically analyzed. Results 21 patients sustained 32 subsequent fractures. 18 vertebras were classified as adjacent fractures. Lower BMD,intradiscal cement leakage and greater restoration rate of vertebral height were the significantly predictive factors of the frac- ture. Conclusion Lower BMD,intradiscal cement leakage and greater restoration rate of vertebral height were confirmed as risk factors for newly developed vertebral compression fractures after PVP. The prescription of anti-osteoporotic medication postoperation could lower the incidence of newly developed vertebral compression fractures.

关 键 词：椎体成形术 再发骨折 骨质疏松 

分 类 号：R589[医药卫生—内分泌]